ENSMUSG00000021504


Mus musculus

Features
Gene ID: ENSMUSG00000021504
  
Biological name :B4galt7
  
Synonyms : B4galt7 / Beta-1,4-galactosyltransferase 7 Xylosylprotein 4-beta-galactosyltransferase / Q8R087
  
Possible biological names infered from orthology : beta-1,4-galactosyltransferase 7 / Q9UBV7
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: B1
Gene start: 55599896
Gene end: 55610443
  
Corresponding Affymetrix probe sets: 10405495 (MoGene1.0st)   1426303_at (Mouse Genome 430 2.0 Array)   1426304_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068532
Ensembl peptide - ENSMUSP00000098327
Ensembl peptide - ENSMUSP00000123292
NCBI entrez gene - 218271     See in Manteia.
MGI - MGI:2384987
RefSeq - NM_001311137
RefSeq - NM_146045
RefSeq Peptide - NP_001298066
RefSeq Peptide - NP_666157
swissprot - Q8R087
swissprot - Q3TAW1
swissprot - D3Z065
Ensembl - ENSMUSG00000021504
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galt7ENSDARG00000021899Danio rerio
 B4GALT7ENSGALG00000032145Gallus gallus
 Q9UBV7ENSG00000027847Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JMK0 / B4galt5 / Beta-1,4-galactosyltransferase 5 / O43286*ENSMUSG0000001792928
P15535 / B4galt1 / Beta-1,4-galactosyltransferase 1 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetyl...ENSMUSG0000002841328
Q9Z2Y2 / B4galt2 / Beta-1,4-galactosyltransferase 2 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetyl...ENSMUSG0000002854128
Q91YY2 / B4galt3 / Beta-1,4-galactosyltransferase 3 N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetylglucosaminyl-glycolipid bet...ENSMUSG0000005242328
Q9WVK5 / B4galt6 / Beta-1,4-galactosyltransferase 6 Glucosylceramide beta-1,4-galactosyltransferase / Q9UBX8* / beta-1,4-galactosyltransferase 6*ENSMUSG0000005612427
Q9JJ04 / B4galt4 / Beta-1,4-galactosyltransferase 4 N-acetyllactosamine synthase Lactotriaosylceramide beta-1,4-galactosyltransferase / O60513* / beta-1,4-galactosyltransferase 4*ENSMUSG0000002279326


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006024 glycosaminoglycan biosynthetic process IEA
 biological_processGO:0006029 proteoglycan metabolic process ISS
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation ISS
 biological_processGO:0097435 supramolecular fiber organization ISS
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA
 molecular_functionGO:0008378 galactosyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0046525 xylosylprotein 4-beta-galactosyltransferase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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