Manteia

ENSMUSG00000017929

Mus musculus

Features

Gene ID:	ENSMUSG00000017929

Biological name :	B4galt5

Synonyms :	B4galt5 / Beta-1,4-galactosyltransferase 5 / Q9JMK0

Possible biological names infered from orthology :	O43286

Species:	Mus musculus

Chr. number:	2
Strand:	-1
Band:	H3
Gene start:	167298444
Gene end:	167349183

Corresponding Affymetrix probe sets:	10489891 (MoGene1.0st) 1421967_at (Mouse Genome 430 2.0 Array) 1433617_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000104844 Ensembl peptide - ENSMUSP00000118229 NCBI entrez gene - 56336 See in Manteia. MGI - MGI:1927169 RefSeq - NM_019835 RefSeq Peptide - NP_062809 swissprot - F6XV02 swissprot - Q9JMK0 Ensembl - ENSMUSG00000017929

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9WVK5 / B4galt6 / Beta-1,4-galactosyltransferase 6 Glucosylceramide beta-1,4-galactosyltransferase / Q9UBX8* / beta-1,4-galactosyltransferase 6*	ENSMUSG00000056124	70
P15535 / B4galt1 / Beta-1,4-galactosyltransferase 1 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetyl...	ENSMUSG00000028413	36
Q91YY2 / B4galt3 / Beta-1,4-galactosyltransferase 3 N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetylglucosaminyl-glycolipid bet...	ENSMUSG00000052423	34
Q9JJ04 / B4galt4 / Beta-1,4-galactosyltransferase 4 N-acetyllactosamine synthase Lactotriaosylceramide beta-1,4-galactosyltransferase / O60513* / beta-1,4-galactosyltransferase 4*	ENSMUSG00000022793	32
Q9Z2Y2 / B4galt2 / Beta-1,4-galactosyltransferase 2 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetyl...	ENSMUSG00000028541	32
Q8R087 / B4galt7 / Beta-1,4-galactosyltransferase 7 Xylosylprotein 4-beta-galactosyltransferase / Q9UBV7* / beta-1,4-galactosyltransferase 7*	ENSMUSG00000021504	24

Protein motifs (from Interpro)

Interpro ID	Name
IPR003859	Beta-1,4-galactosyltransferase
IPR027791	Galactosyltransferase, C-terminal
IPR027995	Galactosyltransferase, N-terminal
IPR029044	Nucleotide-diphospho-sugar transferases

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0005975	carbohydrate metabolic process	IEA
biological_process	GO:0006486	protein glycosylation	IEA
cellular_component	GO:0005794	Golgi apparatus	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0032580	Golgi cisterna membrane	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0016757	transferase activity, transferring glycosyl groups	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Keratan sulfate biosynthesis

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001363	increased anxiety-related response	"when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]	Show Allelic Composition: Casp9^tm1Flv/Casp9^tm1Flv Genetic Background: B6.129S1-Casp9^tm1Flv
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Casp9^tm1Flv/Casp9^tm1Flv Genetic Background: B6.129S1-Casp9^tm1Flv
MP:0010166	increased response to stress-induced hyperthermia	"greater increase or faster than expected increase in core body termperature in response to stress or anticipatory anxiety" [PMID:18722480]	Show Allelic Composition: Casp9^tm1Flv/Casp9^tm1Flv Genetic Background: B6.129S1-Casp9^tm1Flv
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Casp9^tm1Flv/Casp9^tm1Flv Genetic Background: B6.129S1-Casp9^tm1Flv
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Casp9^tm1Flv/Casp9^tm1Flv Genetic Background: B6.129S1-Casp9^tm1Flv

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000017929	Q9JMK0 / B4galt5 / Beta-1,4-galactosyltransferase 5 / O43286*	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr