ENSMUSG00000021536


Mus musculus

Features
Gene ID: ENSMUSG00000021536
  
Biological name :Adcy2
  
Synonyms : Adcy2 / adenylate cyclase 2
  
Possible biological names infered from orthology : Q08462
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B3
Gene start: 68620043
Gene end: 68999541
  
Corresponding Affymetrix probe sets: 10410408 (MoGene1.0st)   1455462_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022013
NCBI entrez gene - 210044     See in Manteia.
MGI - MGI:99676
RefSeq - NM_153534
RefSeq Peptide - NP_705762
swissprot - Q3V1Q3
Ensembl - ENSMUSG00000021536
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adcy2aENSDARG00000058392Danio rerio
 adcy2bENSDARG00000014588Danio rerio
 ADCY2ENSGALG00000013060Gallus gallus
 ADCY2ENSG00000078295Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adcy4 / Q91WF3 / Adenylate cyclase type 4 / Q8NFM4* / adenylate cyclase 4*ENSMUSG0000002222056
Adcy7 / P51829 / Adenylate cyclase type 7 / P51828* / adenylate cyclase 7*ENSMUSG0000003165953
Adcy5 / P84309 / Adenylate cyclase type 5 / O95622* / adenylate cyclase 5*ENSMUSG0000002284038
Adcy6 / adenylate cyclase 6 / O43306*ENSMUSG0000002299437
Adcy8 / P97490 / Adenylate cyclase type 8 / P40145* / adenylate cyclase 8*ENSMUSG0000002237635
Adcy1 / O88444 / Adenylate cyclase type 1 / Q08828* / adenylate cyclase 1*ENSMUSG0000002043134
Adcy3 / Q8VHH7 / Adenylate cyclase type 3 / O60266* / adenylate cyclase 3*ENSMUSG0000002065433
Adcy9 / P51830 / Adenylate cyclase type 9 / O60503* / adenylate cyclase 9*ENSMUSG0000000558027


Protein motifs (from Interpro)
Interpro ID Name
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR009398  Adenylate cyclase, conserved domain
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR029787  Nucleotide cyclase
 IPR030672  Adenylate cyclase
 IPR032628  Adenylate cyclase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006171 cAMP biosynthetic process IEA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004016 adenylate cyclase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glucagon signaling in metabolic regulation
PKA activation
PKA activation in glucagon signalling
Adenylate cyclase activating pathway
Adenylate cyclase inhibitory pathway
G alpha (s) signalling events
G alpha (z) signalling events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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