ENSMUSG00000021546


Mus musculus

Features
Gene ID: ENSMUSG00000021546
  
Biological name :Hnrnpk
  
Synonyms : Heteroous nuclear ribonucleoprotein K / Hnrnpk / P61979
  
Possible biological names infered from orthology : heterogeneous nuclear ribonucleoprotein K / P61978
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B1
Gene start: 58391142
Gene end: 58403343
  
Corresponding Affymetrix probe sets: 10409689 (MoGene1.0st)   10409709 (MoGene1.0st)   10410970 (MoGene1.0st)   10554701 (MoGene1.0st)   1423684_at (Mouse Genome 430 2.0 Array)   1448176_a_at (Mouse Genome 430 2.0 Array)   1454692_x_at (Mouse Genome 430 2.0 Array)   1460547_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153253
Ensembl peptide - ENSMUSP00000153320
Ensembl peptide - ENSMUSP00000153705
Ensembl peptide - ENSMUSP00000153651
Ensembl peptide - ENSMUSP00000153523
Ensembl peptide - ENSMUSP00000153487
Ensembl peptide - ENSMUSP00000153416
Ensembl peptide - ENSMUSP00000039269
Ensembl peptide - ENSMUSP00000112104
Ensembl peptide - ENSMUSP00000134837
Ensembl peptide - ENSMUSP00000135109
Ensembl peptide - ENSMUSP00000135305
Ensembl peptide - ENSMUSP00000135342
Ensembl peptide - ENSMUSP00000135354
Ensembl peptide - ENSMUSP00000135407
Ensembl peptide - ENSMUSP00000135623
Ensembl peptide - ENSMUSP00000135647
Ensembl peptide - ENSMUSP00000135833
Ensembl peptide - ENSMUSP00000135867
Ensembl peptide - ENSMUSP00000152935
Ensembl peptide - ENSMUSP00000153054
NCBI entrez gene - 15387     See in Manteia.
MGI - MGI:99894
RefSeq - XM_017315396
RefSeq - NM_001301340
RefSeq - NM_001301341
RefSeq - NM_001301343
RefSeq - NM_001301344
RefSeq - NM_001301345
RefSeq - NM_025279
RefSeq - XM_006517103
RefSeq - XM_006517104
RefSeq - XM_006517106
RefSeq - XM_017315395
RefSeq Peptide - NP_001288272
RefSeq Peptide - NP_001288273
RefSeq Peptide - NP_001288274
RefSeq Peptide - NP_079555
RefSeq Peptide - NP_001288269
RefSeq Peptide - NP_001288270
swissprot - A0A286YEC4
swissprot - A0A286YE41
swissprot - A0A286YDM3
swissprot - A0A286YDH1
swissprot - H3BJ43
swissprot - H3BJS9
swissprot - H3BK96
swissprot - H3BKD0
swissprot - H3BKI8
swissprot - H3BLP7
swissprot - H3BLL4
swissprot - A0A286YCM2
swissprot - P61979
swissprot - Q5FWJ5
swissprot - Q8BT23
swissprot - B2M1R6
Ensembl - ENSMUSG00000021546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnpkENSDARG00000018914Danio rerio
 hnrpklENSDARG00000007034Danio rerio
 ENSGALG00000012591Gallus gallus
 Q5ZIQ3ENSGALG00000040086Gallus gallus
 HNRNPKENSG00000165119Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcbp2 / Q61990 / Poly(rC)-binding protein 2 ENSMUSG0000005685126
Pcbp3 / P57722 / Mus musculus poly(rC) binding protein 3 (Pcbp3), transcript variant 2, mRNA. / P57721* / poly(rC) binding protein 3*ENSMUSG0000000112025
Pcbp1 / P60335 / Poly(rC)-binding protein 1 / Q15365*ENSMUSG0000005169524
Nova1 / Q9JKN6 / RNA-binding protein Nova-1 / P51513* / NOVA alternative splicing regulator 1*ENSMUSG0000002104723
Nova2 / NOVA alternative splicing regulator 2 / Q9UNW9*ENSMUSG0000003041123
Pcbp4 / poly(rC) binding protein 4 / P57723*ENSMUSG0000002349521


Protein motifs (from Interpro)
Interpro ID Name
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR012987  ROK, N-terminal
 IPR033090  Heterogeneous nuclear ribonucleoprotein K
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010988 regulation of low-density lipoprotein particle clearance ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IMP
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis ISO
 biological_processGO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter ISO
 biological_processGO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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