ENSMUSG00000024084


Mus musculus

Features
Gene ID: ENSMUSG00000024084
  
Biological name :Qpct
  
Synonyms : glutaminyl-peptide cyclotransferase (glutaminyl cyclase) / Qpct
  
Possible biological names infered from orthology : glutaminyl-peptide cyclotransferase / Q16769
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: E3
Gene start: 79051906
Gene end: 79090243
  
Corresponding Affymetrix probe sets: 10447056 (MoGene1.0st)   1426622_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038732
NCBI entrez gene - 70536     See in Manteia.
MGI - MGI:1917786
RefSeq - NM_001316729
RefSeq - NM_027455
RefSeq Peptide - NP_081731
RefSeq Peptide - NP_001303658
swissprot - A0A0R4J0G6
Ensembl - ENSMUSG00000024084
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 qpctENSDARG00000089717Danio rerio
 QPCTENSGALG00000032440Gallus gallus
 QPCTENSG00000115828Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Qpctl / Q8BH73 / Glutaminyl-peptide cyclotransferase-like protein / Q9NXS2* / glutaminyl-peptide cyclotransferase like*ENSMUSG0000003040747


Protein motifs (from Interpro)
Interpro ID Name
 IPR007484  Peptidase M28
 IPR037457  M28 Zn-Peptidase Glutaminyl Cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016603 glutaminyl-peptide cyclotransferase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003329 amyloid beta deposits 
Show

Allelic Composition: Hoxa5tm1Rob/Hoxa5tm1Rob,Pdgfratm11(EGFP)Sor/Pdgfra+
Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * MF1

Allelic Composition: Qpcttm1.2Tbay/Qpcttm1.2Tbay,Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2Tg(Thy1-Trh/APP*)2.1Ingm
Genetic Background: involves: 129S2/SvPas * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr