ENSMUSG00000030407


Mus musculus

Features
Gene ID: ENSMUSG00000030407
  
Biological name :Qpctl
  
Synonyms : Glutaminyl-peptide cyclotransferase-like protein / Q8BH73 / Qpctl
  
Possible biological names infered from orthology : glutaminyl-peptide cyclotransferase like / Q9NXS2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 19139702
Gene end: 19149291
  
Corresponding Affymetrix probe sets: 10560434 (MoGene1.0st)   1449517_at (Mouse Genome 430 2.0 Array)   1449518_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032566
NCBI entrez gene - 67369     See in Manteia.
MGI - MGI:1914619
RefSeq - NM_026111
RefSeq Peptide - NP_080387
swissprot - Q8BH73
Ensembl - ENSMUSG00000030407
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 qpctlaENSDARG00000061691Danio rerio
 qpctlbENSDARG00000062293Danio rerio
 QPCTLENSG00000011478Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Qpct / glutaminyl-peptide cyclotransferase (glutaminyl cyclase) / Q16769* / glutaminyl-peptide cyclotransferase*ENSMUSG0000002408444


Protein motifs (from Interpro)
Interpro ID Name
 IPR007484  Peptidase M28
 IPR037457  M28 Zn-Peptidase Glutaminyl Cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016603 glutaminyl-peptide cyclotransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003329 amyloid beta deposits 
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Allelic Composition: Qpcttm1.2Tbay/Qpcttm1.2Tbay,Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2Tg(Thy1-Trh/APP*)2.1Ingm
Genetic Background: involves: 129S2/SvPas * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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