ENSMUSG00000025075


Mus musculus

Features
Gene ID: ENSMUSG00000025075
  
Biological name :Habp2
  
Synonyms : Habp2 / Mus musculus hyaluronic acid binding protein 2 (Habp2), transcript variant 1, mRNA.
  
Possible biological names infered from orthology : hyaluronan binding protein 2 / Q14520
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D2
Gene start: 56287137
Gene end: 56320822
  
Corresponding Affymetrix probe sets: 10464113 (MoGene1.0st)   1443695_at (Mouse Genome 430 2.0 Array)   1443696_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128964
Ensembl peptide - ENSMUSP00000126235
Ensembl peptide - ENSMUSP00000130809
Ensembl peptide - ENSMUSP00000132444
Ensembl peptide - ENSMUSP00000077402
Ensembl peptide - ENSMUSP00000093641
NCBI entrez gene - 226243     See in Manteia.
MGI - MGI:1196378
RefSeq - XM_017318167
RefSeq - NM_001329935
RefSeq - NM_146101
RefSeq - XM_006527014
RefSeq Peptide - NP_666213
RefSeq Peptide - NP_001316864
swissprot - E9Q092
swissprot - E9QM92
swissprot - F7B276
swissprot - E9Q0C5
swissprot - F7D2A6
swissprot - Q3V1J8
Ensembl - ENSMUSG00000025075
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 habp2ENSDARG00000057498Danio rerio
 HABP2ENSGALG00000008905Gallus gallus
 HABP2ENSG00000148702Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hgfac / Q9R098 / hepatocyte growth factor activator / Q04756* / HGF activator*ENSMUSG0000002910236
F12 / Q80YC5 / Coagulation factor XII Coagulation factor XIIa heavy chain Coagulation factor XIIa light chain / P00748* / coagulation factor XII*ENSMUSG0000002149232
Plat / P11214 / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B / P00750* / plasminogen activator, tissue type*ENSMUSG0000003153832
Plg / P20918 / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B / LPA* / P00747* / P08519* / plasminogen* / lipoprotein(a)*ENSMUSG0000005948132
Plau / P06869 / plasminogen activator, urokinase / P00749*ENSMUSG0000002182229
F2 / P19221 / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain / P00734* / coagulation factor II, thrombin*ENSMUSG0000002724926
Mst1 / P26928 / macrophage stimulating 1 (hepatocyte growth factor-like) / macrophage stimulating 1*ENSMUSG0000003259126
Hgf / Q08048 / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain / P14210* / hepatocyte growth factor*ENSMUSG0000002886425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000742  EGF-like domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR001881  EGF-like calcium-binding domain
 IPR009003  Peptidase S1, PA clan
 IPR012224  Peptidase S1A, coagulation factor VII/IX/X/C/Z
 IPR013032  EGF-like, conserved site
 IPR013806  Kringle-like fold
 IPR018056  Kringle, conserved site
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007596 blood coagulation IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Tll1b2b2476Clo/Tll1b2b2476Clo
Genetic Background: C57BL/6J-Tll1b2b2476Clo

 MP:0003333 liver fibrosis "invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Tll1b2b2476Clo/Tll1b2b2476Clo
Genetic Background: C57BL/6J-Tll1b2b2476Clo

 MP:0005164 abnormal response to injury "anomaly in the body s reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tll1b2b2476Clo/Tll1b2b2476Clo
Genetic Background: C57BL/6J-Tll1b2b2476Clo

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tll1b2b2476Clo/Tll1b2b2476Clo
Genetic Background: C57BL/6J-Tll1b2b2476Clo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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