ENSMUSG00000025401


Mus musculus

Features
Gene ID: ENSMUSG00000025401
  
Biological name :Myo1a
  
Synonyms : Myo1a / O88329 / Unconventional myosin-Ia
  
Possible biological names infered from orthology : myosin IA / Q9UBC5
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 127705170
Gene end: 127720940
  
Corresponding Affymetrix probe sets: 10366994 (MoGene1.0st)   1429805_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078540
NCBI entrez gene - 432516     See in Manteia.
MGI - MGI:107732
RefSeq - XM_006513860
RefSeq - NM_001081219
RefSeq - XM_006513859
RefSeq Peptide - NP_001074688
swissprot - O88329
Ensembl - ENSMUSG00000025401
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYO1AENSGALG00000032598Gallus gallus
 MYO1AENSG00000166866Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo1b / P46735 / myosin IB / O43795*ENSMUSG0000001841759
Myo1c / Q9WTI7 / Unconventional myosin-Ic / O00159* / myosin IC*ENSMUSG0000001777442
Myo1d / Q5SYD0 / Unconventional myosin-Id / O94832* / myosin ID*ENSMUSG0000003544139
Myo1h / Q9D6A1 / Unconventional myosin-Ih / Q8N1T3* / myosin IH*ENSMUSG0000006695239
Myo1g / Q5SUA5 / Unconventional myosin-Ig / B0I1T2* / myosin IG*ENSMUSG0000002043737
Myo1e / E9Q634 / Unconventional myosin-Ie / Q12965* / myosin IE*ENSMUSG0000003222036
Myo1f / myosin IF / O00160*ENSMUSG0000002430035
Myo15 / Q9QZZ4 / Unconventional myosin-XV / MYO15A* / Q9UKN7* / myosin XVA*ENSMUSG0000004267831
Myo15b / myosin XVBENSMUSG0000003442726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR010926  Class I myosin tail homology domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036072  Class I myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0030030 cell projection organization IMP
 biological_processGO:0030033 microvillus assembly IMP
 biological_processGO:0051648 vesicle localization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0044853 plasma membrane raft IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008142 decreased small intestinal villus size "reduced size of the tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Wnt9btm1Amc/Wnt9btm1Amc
Genetic Background: involves: 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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