ENSMUSG00000025480


Mus musculus

Features
Gene ID: ENSMUSG00000025480
  
Biological name :Syce1
  
Synonyms : Q9D495 / Syce1 / Synaptonemal complex central element protein 1
  
Possible biological names infered from orthology : Q8N0S2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F4
Gene start: 140777229
Gene end: 140787852
  
Corresponding Affymetrix probe sets: 10568968 (MoGene1.0st)   1428685_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148137
Ensembl peptide - ENSMUSP00000026553
NCBI entrez gene - 74075     See in Manteia.
MGI - MGI:1921325
RefSeq - NM_001143765
RefSeq Peptide - NP_001137237
swissprot - A0A1B0GSZ8
swissprot - Q9D495
Ensembl - ENSMUSG00000025480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SYCE1ENSG00000171772Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5D525 / Syce1l / Synaptonemal complex central element protein 1-like / A8MT33*ENSMUSG0000003340927


Protein motifs (from Interpro)
Interpro ID Name
 IPR026676  Synaptonemal complex central element protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007128 meiotic prophase I IEA
 biological_processGO:0007130 synaptonemal complex assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0070193 synaptonemal complex organization IEA
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0000801 central element IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002682 reduced number of mature ovarian follicles "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0009452 abnormal synaptonemal complex "an anomaly in the formation of the proteinaceous structure involved in the pairing of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003824 Syce2 / Q505B8 / Synaptonemal complex central element protein 2 / Q6PIF2*  / complex
 ENSMUSG00000032065 Tex12 / Q9CR81 / Testis-expressed protein 12 / Q9BXU0* / testis expressed 12*  / complex
 ENSMUSG00000078938 Syce3 / B5KM66 / Synaptonemal complex central element protein 3 / A1L190*  / complex






 

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