ENSMUSG00000032065


Mus musculus

Features
Gene ID: ENSMUSG00000032065
  
Biological name :Tex12
  
Synonyms : Q9CR81 / Testis-expressed protein 12 / Tex12
  
Possible biological names infered from orthology : Q9BXU0 / testis expressed 12
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.3
Gene start: 50556819
Gene end: 50561325
  
Corresponding Affymetrix probe sets: 10593347 (MoGene1.0st)   1421183_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034568
Ensembl peptide - ENSMUSP00000149921
NCBI entrez gene - 66654     See in Manteia.
MGI - MGI:1913904
RefSeq - NM_025687
RefSeq Peptide - NP_079963
swissprot - Q9CR81
Ensembl - ENSMUSG00000032065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TEX12ENSG00000150783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029193  Testis-expressed sequence 12 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000711 meiotic DNA repair synthesis IMP
 biological_processGO:0007130 synaptonemal complex assembly IMP
 cellular_componentGO:0000795 synaptonemal complex ISS
 cellular_componentGO:0000801 central element IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0001132 absent mature ovarian follicles "failure of ovarian follicle differentiation" [J:35782]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0002682 reduced number of mature ovarian follicles "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0005431 oocyte depletion "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

 MP:0008966 abnormal chiasmata formation "atypical contact between nonsister chromatids of homologous chromosomes during meiosis I, precluding formation of the expected number of cross-shaped configurations representing recombination events" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Asphtm1Egk/Asphtm1Egk
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003824 Syce2 / Q505B8 / Synaptonemal complex central element protein 2 / Q6PIF2*  / complex
 ENSMUSG00000025480 Syce1 / Q9D495 / Synaptonemal complex central element protein 1 / Q8N0S2*  / complex
 ENSMUSG00000078938 Syce3 / B5KM66 / Synaptonemal complex central element protein 3 / A1L190*  / complex






 

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