ENSMUSG00000025787


Mus musculus

Features
Gene ID: ENSMUSG00000025787
  
Biological name :Tgm4
  
Synonyms : Tgm4 / transglutaminase 4
  
Possible biological names infered from orthology : P49221
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 123034726
Gene end: 123067561
  
Corresponding Affymetrix probe sets: 10590533 (MoGene1.0st)   1438341_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026893
Ensembl peptide - ENSMUSP00000149120
Ensembl peptide - ENSMUSP00000149061
NCBI entrez gene - 331046     See in Manteia.
MGI - MGI:3027002
RefSeq - NM_177911
RefSeq - XM_017313442
RefSeq Peptide - NP_808579
swissprot - A0A1L1SQH9
swissprot - A0A0R4J071
swissprot - A0A1L1SQM7
Ensembl - ENSMUSG00000025787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TGM4ENSGALG00000033171Gallus gallus
 TGM4ENSG00000163810Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tgm6 / transglutaminase 6 / O95932*ENSMUSG0000002740335
Tgm1 / transglutaminase 1 / P22735*ENSMUSG0000002221834
F13a1 / Q8BH61 / Coagulation factor XIII A chain / P00488*ENSMUSG0000003910934
Tgm3 / Q08189 / Protein-glutamine gamma-glutamyltransferase E Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain Protein-glutamine gamma-glutamyltransferase E 27 kDa non-ca...ENSMUSG0000002740132
Tgm5 / Q9D7I9 / Protein-glutamine gamma-glutamyltransferase 5 / O43548* / transglutaminase 5*ENSMUSG0000005367532
Tgm7 / protein-glutamine gamma-glutamyltransferase Z / Q96PF1* / transglutaminase 7*ENSMUSG0000007910331
Tgm2 / P21981 / Protein-glutamine gamma-glutamyltransferase 2 / P21980* / transglutaminase 2*ENSMUSG0000003782030
Epb42 / P49222 / Erythrocyte membrane protein band 4.2 / P16452*ENSMUSG0000002321626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001102  Transglutaminase, N-terminal
 IPR002931  Transglutaminase-like
 IPR008958  Transglutaminase, C-terminal
 IPR013783  Immunoglobulin-like fold
 IPR013808  Transglutaminase, active site
 IPR014756  Immunoglobulin E-set
 IPR023608  Protein-glutamine gamma-glutamyltransferase, animal
 IPR036238  Transglutaminase, C-terminal domain superfamily
 IPR036985  Transglutaminase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018149 peptide cross-linking IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0003810 protein-glutamine gamma-glutamyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cdkn2atm2.1Brn/Cdkn2atm2.1Brn,Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn2atm2.1Brn/Cdkn2atm2.1Brn,Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr