ENSMUSG00000026277


Mus musculus

Features
Gene ID: ENSMUSG00000026277
  
Biological name :Stk25
  
Synonyms : Q9Z2W1 / Serine/threonine-protein kinase 25 / Stk25
  
Possible biological names infered from orthology : O00506 / serine/threonine kinase 25
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: D
Gene start: 93619751
Gene end: 93658659
  
Corresponding Affymetrix probe sets: 10356833 (MoGene1.0st)   1416770_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027498
Ensembl peptide - ENSMUSP00000140396
Ensembl peptide - ENSMUSP00000117765
NCBI entrez gene - 59041     See in Manteia.
MGI - MGI:1891699
RefSeq - NM_021537
RefSeq - XM_006529768
RefSeq Peptide - NP_067512
swissprot - D3Z359
swissprot - Q9Z2W1
swissprot - A0A087WQY6
Ensembl - ENSMUSG00000026277
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk25aENSDARG00000002210Danio rerio
 stk25bENSDARG00000039022Danio rerio
 STK25ENSGALG00000037739Gallus gallus
 STK25ENSG00000115694Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stk24 / Q99KH8 / serine/threonine kinase 24 / Q9Y6E0*ENSMUSG0000006341074
Stk26 / Q99JT2 / serine/threonine kinase 26 / Q9P289*ENSMUSG0000003111267
Stk3 / Q9JI10 / Mus musculus serine/threonine kinase 3 (Stk3), transcript variant 2, mRNA. / Q13188* / serine/threonine kinase 3*ENSMUSG0000002232942
Stk4 / Q9JI11 / serine/threonine kinase 4 / Q13043*ENSMUSG0000001820941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR035060  Serine/threonine kinase 25, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IMP
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0050772 positive regulation of axonogenesis IMP
 biological_processGO:0051645 Golgi localization IEA
 biological_processGO:0051683 establishment of Golgi localization IEA
 biological_processGO:0090168 Golgi reassembly IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rapgef3tm1.1Chen/Rapgef3tm1.1Chen
Genetic Background: B6.129(Cg)-Rapgef3tm1.1Chen

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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