ENSDARG00000039022


Danio rerio

Features
Gene ID: ENSDARG00000039022
  
Biological name :stk25b
  
Synonyms : serine/threonine kinase 25b / stk25b
  
Possible biological names infered from orthology : O00506 / Q9Z2W1 / serine/threonine kinase 25 / Serine/threonine-protein kinase 25 / STK25
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 22617675
Gene end: 22636721
  
Corresponding Affymetrix probe sets: Dr.2519.1.S1_at (Zebrafish Array)   NM_213308_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056962
Ensembl peptide - ENSDARP00000115867
NCBI entrez gene - 406600     See in Manteia.
RefSeq - NM_213308
RefSeq - XM_005171203
RefSeq Peptide - NP_998473
swissprot - Q7ZVG8
swissprot - F1Q6B7
ZFIN ID - ZDB-GENE-040426-2537
Ensembl - ENSDARG00000039022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STK25ENSGALG00000037739Gallus gallus
 STK25ENSG00000115694Homo sapiens
 Stk25ENSMUSG00000026277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stk25a / serine/threonine kinase 25a / STK25* / Q9Z2W1* / O00506* / serine/threonine kinase 25* / Serine/threonine-protein kinase 25 *ENSDARG0000000221083
stk24b / serine/threonine kinase 24b (STE20 homolog, yeast) / STK24* / Q99KH8* / Q9Y6E0* / serine/threonine kinase 24*ENSDARG0000002387871
stk26 / serine/threonine protein kinase 26 / Q9P289* / serine/threonine kinase 26*ENSDARG0000006039069
stk24a / serine/threonine kinase 24a (STE20 homolog, yeast) / STK24* / Q9Y6E0* / serine/threonine kinase 24*ENSDARG0000010095568
stk3 / Q7ZUQ3 / serine/threonine kinase 3 (STE20 homolog, yeast) / Q13188* / Q9JI10* / serine/threonine kinase 3* / Mus musculus serine/threonine kinase 3 (Stk3), transcript variant 2, mRNA.*ENSDARG0000001131240


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007507 heart development IGI
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0048812 neuron projection morphogenesis IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0001067 anterior cerebral vein anterior cerebral vein dilated , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus edematous , abnormal
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 ZFA:0005049 prosencephalic artery prosencephalic artery dilated , abnormal
Show

 ZFA:0005092 mesencephalic vein mesencephalic vein spatial pattern , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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