ENSMUSG00000026723


Mus musculus

Features
Gene ID: ENSMUSG00000026723
  
Biological name :Trdmt1
  
Synonyms : O55055 / Trdmt1 / tRNA (cytosine(38)-C(5))-methyltransferase
  
Possible biological names infered from orthology : O14717 / tRNA aspartic acid methyltransferase 1
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 13509014
Gene end: 13544668
  
Corresponding Affymetrix probe sets: 10480224 (MoGene1.0st)   1419749_at (Mouse Genome 430 2.0 Array)   1419750_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114572
Ensembl peptide - ENSMUSP00000141758
NCBI entrez gene - 13434     See in Manteia.
MGI - MGI:1274787
RefSeq - XM_011238948
RefSeq - NM_010067
RefSeq - XM_006497324
RefSeq - XM_006497325
RefSeq - XM_006497326
RefSeq Peptide - NP_034197
swissprot - A0A0A6YWY7
swissprot - O55055
swissprot - Q5I0V6
Ensembl - ENSMUSG00000026723
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trdmt1ENSDARG00000034518Danio rerio
 TRDMT1ENSGALG00000008686Gallus gallus
 O14717ENSG00000107614Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001525  C-5 cytosine methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR031303  DNA methylase, C-5 cytosine-specific, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation ISO
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008175 tRNA methyltransferase activity ISO
 molecular_functionGO:0016428 tRNA (cytosine-5-)-methyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hdac7tm1Eno/Hdac7tm2Eno,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
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Allelic Composition: Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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