ENSMUSG00000026866


Mus musculus

Features
Gene ID: ENSMUSG00000026866
  
Biological name :Kynu
  
Synonyms : Kynu / kynureninase
  
Possible biological names infered from orthology : Q16719
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 43555329
Gene end: 43682715
  
Corresponding Affymetrix probe sets: 10471912 (MoGene1.0st)   1430570_at (Mouse Genome 430 2.0 Array)   1451903_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108445
Ensembl peptide - ENSMUSP00000028223
Ensembl peptide - ENSMUSP00000061775
NCBI entrez gene - 70789     See in Manteia.
MGI - MGI:1918039
RefSeq - XM_011239179
RefSeq - NM_001289593
RefSeq - NM_001289594
RefSeq - NM_027552
RefSeq - XM_006498325
RefSeq - XM_011239178
RefSeq Peptide - NP_001276523
RefSeq Peptide - NP_081828
RefSeq Peptide - NP_001276522
swissprot - A2ARD7
swissprot - Q6NSV5
swissprot - A2ARD6
Ensembl - ENSMUSG00000026866
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kynuENSDARG00000099546Danio rerio
 ENSGALG00000012418Gallus gallus
 KYNUENSG00000115919Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000192  Aminotransferase class V domain
 IPR010111  Kynureninase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006569 tryptophan catabolic process IEA
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019441 tryptophan catabolic process to kynurenine IEA
 biological_processGO:0019442 tryptophan catabolic process to acetyl-CoA IEA
 biological_processGO:0019805 quinolinate biosynthetic process IEA
 biological_processGO:0034341 response to interferon-gamma IEA
 biological_processGO:0034354 "de novo" NAD biosynthetic process from tryptophan IEA
 biological_processGO:0034516 response to vitamin B6 IEA
 biological_processGO:0043420 anthranilate metabolic process IEA
 biological_processGO:0097053 L-kynurenine catabolic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0030429 kynureninase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0061981 3-hydroxykynureninase activity IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026866 Kynu / kynureninase / Q16719*  / complex






 

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