ENSMUSG00000027072


Mus musculus

Features
Gene ID: ENSMUSG00000027072
  
Biological name :Prg3
  
Synonyms : Prg3 / Proteoglycan 3 / Q9JL95
  
Possible biological names infered from orthology : proteoglycan 3, pro eosinophil major basic protein 2 / Q9Y2Y8
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: D
Gene start: 84988215
Gene end: 84993886
  
Corresponding Affymetrix probe sets: 10473406 (MoGene1.0st)   1449924_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028466
NCBI entrez gene - 53856     See in Manteia.
MGI - MGI:1858200
RefSeq - NM_016914
RefSeq - XM_006499901
RefSeq Peptide - NP_058610
swissprot - Q9JL95
Ensembl - ENSMUSG00000027072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGR2/3ENSGALG00000043860Gallus gallus
 PRG3ENSG00000156575Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prg2 / Q61878 / proteoglycan 2, bone marrow / P13727* / proteoglycan 2, pro eosinophil major basic protein*ENSMUSG0000002707352


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR002352  Eosinophil major basic protein
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033816  Eosinophil major basic protein, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001694 histamine biosynthetic process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0019370 leukotriene biosynthetic process IEA
 biological_processGO:0042035 regulation of cytokine biosynthetic process IBA
 biological_processGO:0042119 neutrophil activation IEA
 biological_processGO:0042554 superoxide anion generation IEA
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process IEA
 biological_processGO:0045575 basophil activation IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002942 decreased circulating alanine transaminase level "decreased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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