ENSMUSG00000027073


Mus musculus

Features
Gene ID: ENSMUSG00000027073
  
Biological name :Prg2
  
Synonyms : Prg2 / proteoglycan 2, bone marrow / Q61878
  
Possible biological names infered from orthology : P13727 / proteoglycan 2, pro eosinophil major basic protein
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: D
Gene start: 84980461
Gene end: 84983632
  
Corresponding Affymetrix probe sets: 10473399 (MoGene1.0st)   1422873_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028467
NCBI entrez gene - 19074     See in Manteia.
MGI - MGI:103294
RefSeq - NM_008920
RefSeq Peptide - NP_032946
swissprot - Q545D8
swissprot - Q61878
Ensembl - ENSMUSG00000027073
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGR2/3ENSGALG00000043860Gallus gallus
 PRG2ENSG00000186652Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prg3 / Q9JL95 / Proteoglycan 3 / Q9Y2Y8* / proteoglycan 3, pro eosinophil major basic protein 2*ENSMUSG0000002707252


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR002352  Eosinophil major basic protein
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033816  Eosinophil major basic protein, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002215 defense response to nematode IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0032693 negative regulation of interleukin-10 production IMP
 biological_processGO:0032753 positive regulation of interleukin-4 production IMP
 biological_processGO:0042035 regulation of cytokine biosynthetic process IBA
 biological_processGO:0042742 defense response to bacterium IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001845 abnormal inflammatory response "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: Mst1rtm1Sjd/Mst1r+
Genetic Background: either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss)

 MP:0002405 respiratory system inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the respiratory system" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Mst1rtm1Sjd/Mst1r+
Genetic Background: either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss)

 MP:0005061 abnormal eosinophil morphology "structural anomaly of the granular leukocytes having a two-lobed nucleus and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mst1rtm1Sjd/Mst1r+
Genetic Background: either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr