ENSMUSG00000027246


Mus musculus

Features
Gene ID: ENSMUSG00000027246
  
Biological name :Ell3
  
Synonyms : Ell3 / Q80VR2 / RNA polymerase II elongation factor ELL3
  
Possible biological names infered from orthology : elongation factor for RNA polymerase II 3 / Q9HB65
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 121439010
Gene end: 121444278
  
Corresponding Affymetrix probe sets: 10486833 (MoGene1.0st)   1442514_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028679
Ensembl peptide - ENSMUSP00000112133
NCBI entrez gene - 269344     See in Manteia.
MGI - MGI:2673679
RefSeq - NM_145973
RefSeq Peptide - NP_666085
swissprot - Q80VR2
Ensembl - ENSMUSG00000027246
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-13k12.2ENSDARG00000038121Danio rerio
 ELL3ENSG00000128886Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ell2 / Q3UKU1 / RNA polymerase II elongation factor ELL2 / O00472* / elongation factor for RNA polymerase II 2*ENSMUSG0000000154229
Ell / O08856 / RNA polymerase II elongation factor ELL / P55199* / elongation factor for RNA polymerase II*ENSMUSG0000007000228
Q3UZP0 / Marveld2 / MARVEL domain-containing protein 2 / Q8N4S9* / MARVEL domain containing 2*ENSMUSG0000002163614
Ocel1 / occludin/ELL domain containing 1 / Q9H607*ENSMUSG000000023969


Protein motifs (from Interpro)
Interpro ID Name
 IPR010844  Occludin homology domain
 IPR019464  RNA polymerase II elongation factor ELL, N-terminal
 IPR031175  RNA polymerase II elongation factor ELL3
 IPR031176  ELL/occludin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006354 DNA-templated transcription, elongation ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IMP
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter ISO
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation ISO
 biological_processGO:0042795 snRNA transcription by RNA polymerase II ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048863 stem cell differentiation IMP
 biological_processGO:0050769 positive regulation of neurogenesis IDA
 biological_processGO:1901797 negative regulation of signal transduction by p53 class mediator IDA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0008023 transcription elongation factor complex ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035326 enhancer binding IDA


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034525 Ice1 / E9Q286 / Little elongation complex subunit 1 / Q9Y2F5* / interactor of little elongation complex ELL subunit 1*  / complex
 ENSMUSG00000027387 Zc3h8 / Q9JJ48 / zinc finger CCCH type containing 8 / Q8N5P1*  / complex
 ENSMUSG00000032235 Ice2 / Q3UZ18 / Little elongation complex subunit 2 / Q659A1* / interactor of little elongation complex ELL subunit 2*  / complex






 

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