ENSMUSG00000027359


Mus musculus

Features
Gene ID: ENSMUSG00000027359
  
Biological name :Slc27a2
  
Synonyms : O35488 / Slc27a2 / Very long-chain acyl-CoA synthetase
  
Possible biological names infered from orthology : O14975 / solute carrier family 27 member 2
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 126552407
Gene end: 126588243
  
Corresponding Affymetrix probe sets: 10475653 (MoGene1.0st)   1416316_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117145
Ensembl peptide - ENSMUSP00000057595
NCBI entrez gene - 26458     See in Manteia.
MGI - MGI:1347099
RefSeq - NM_011978
RefSeq Peptide - NP_036108
swissprot - A2ANX6
swissprot - O35488
Ensembl - ENSMUSG00000027359
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O14975ENSG00000140284Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slc27a6 / solute carrier family 27 member 6 / Q9Y2P4*ENSMUSG0000002460050
Q4LDG0 / Slc27a5 / Bile acyl-CoA synthetase / Q9Y2P5* / solute carrier family 27 member 5*ENSMUSG0000003038244
Slc27a3 / solute carrier family 27 (fatty acid transporter), member 3 / Q5K4L6* / solute carrier family 27 member 3*ENSMUSG0000002793242
Q60714 / Slc27a1 / solute carrier family 27 (fatty acid transporter), member 1 / Q6PCB7* / solute carrier family 27 member 1*ENSMUSG0000003180838
Q91VE0 / Slc27a4 / Long-chain fatty acid transport protein 4 / Q6P1M0* / solute carrier family 27 member 4*ENSMUSG0000005931638


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain
 IPR030305  Fatty acid transport protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IDA
 biological_processGO:0001561 fatty acid alpha-oxidation IEA
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0006699 bile acid biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0042760 very long-chain fatty acid catabolic process IMP
 biological_processGO:0044539 long-chain fatty acid import IEA
 biological_processGO:0097089 methyl-branched fatty acid metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome TAS
 cellular_componentGO:0005778 peroxisomal membrane ISO
 cellular_componentGO:0005779 integral component of peroxisomal membrane ISS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004467 long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015245 fatty acid transmembrane transporter activity IDA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031957 very long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0050197 phytanate-CoA ligase activity IEA
 molecular_functionGO:0070251 pristanate-CoA ligase activity IEA
 molecular_functionGO:0102391 decanoate-CoA ligase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Alpha-oxidation of phytanate
Neutrophil degranulation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mafftm1.1Jeng/Mafftm1.1Jeng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Abcd1tm1Kds/Abcd1tm1Kds,Slc27a2tm1Kds/Slc27a2tm1Kds
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Abcd1tm1Kds/Y,Slc27a2tm1Kds/Slc27a2tm1Kds
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mafftm1.1Jeng/Mafftm1.1Jeng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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