ENSMUSG00000027790


Mus musculus

Features
Gene ID: ENSMUSG00000027790
  
Biological name :Sis
  
Synonyms : Sis / sucrase-isomaltase
  
Possible biological names infered from orthology : P14410 / SI
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: E3
Gene start: 72888557
Gene end: 72967863
  
Corresponding Affymetrix probe sets: 10498659 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000091742
Ensembl peptide - ENSMUSP00000129116
NCBI entrez gene - 69983     See in Manteia.
MGI - MGI:1917233
RefSeq - NM_001081137
RefSeq - XM_006502044
RefSeq Peptide - NP_001074606
swissprot - F8VQM5
Ensembl - ENSMUSG00000027790
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079192.1ENSDARG00000101629Danio rerio
 CABZ01088484.1ENSDARG00000104569Danio rerio
 ENSGALG00000009511Gallus gallus
 SIENSG00000090402Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mgam / maltase-glucoamylase / O43451*ENSMUSG0000006858759
Gaa / P70699 / Lysosomal alpha-glucosidase / P10253* / glucosidase alpha, acid*ENSMUSG0000002557920
Ganc / glucosidase alpha, neutral C / Q8TET4*ENSMUSG0000006264612
Ganab / Q8BHN3 / Neutral alpha-glucosidase AB / Q14697* / glucosidase II alpha subunit*ENSMUSG0000007165012
Q69ZQ1 / AI464131 / Myosis-regulating glycosidase / MYORG* / Q6NSJ0* / myogenesis regulating glycosidase (putative)*ENSMUSG000000463127


Protein motifs (from Interpro)
Interpro ID Name
 IPR000322  Glycoside hydrolase family 31
 IPR000519  P-type trefoil domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR017853  Glycoside hydrolase superfamily
 IPR017957  P-type trefoil, conserved site
 IPR025887  Glycoside hydrolase family 31, N-terminal domain
 IPR030458  Glycosyl hydrolases family 31, active site
 IPR030459  Glycosyl hydrolases family 31, conserved site
 IPR031727  Galactose mutarotase, N-terminal barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 cellular_componentGO:0005903 brush border TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004558 alpha-1,4-glucosidase activity ISO
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027790 Sis / sucrase-isomaltase / SI* / P14410*  / complex






 

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