Manteia

ENSMUSG00000027983

Mus musculus

Features

Gene ID:	ENSMUSG00000027983

Biological name :	Cyp2u1

Synonyms :	Cyp2u1 / Cytochrome P450 2U1 / Q9CX98

Possible biological names infered from orthology :	cytochrome P450 family 2 subfamily U member 1 / Q7Z449

Species:	Mus musculus

Chr. number:	3
Strand:	-1
Band:	G3
Gene start:	131288441
Gene end:	131303227

Corresponding Affymetrix probe sets:	10502214 (MoGene1.0st) 1442537_at (Mouse Genome 430 2.0 Array) 1444960_at (Mouse Genome 430 2.0 Array) 1453500_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000101944 Ensembl peptide - ENSMUSP00000142519 NCBI entrez gene - 71519 See in Manteia. MGI - MGI:1918769 RefSeq - NM_027816 RefSeq Peptide - NP_082092 swissprot - Q9CX98 Ensembl - ENSMUSG00000027983

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
cyp2u1	ENSDARG00000026548	Danio rerio
CYP2U1	ENSGALG00000027908	Gallus gallus
CYP2U1	ENSG00000155016	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Cyp2r1 / Q6VVW9 / Vitamin D 25-hydroxylase / Q6VVX0* / cytochrome P450 family 2 subfamily R member 1*	ENSMUSG00000030670	38
Cyp2j6 / O54750 / Cytochrome P450 2J6 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000052914	38
Cyp2j9 / cytochrome P450, family 2, subfamily j, polypeptide 9 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000015224	37
Cyp2d26 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*	ENSMUSG00000022445	37
Cyp2j5 / O54749 / Cytochrome P450 2J5 / P51589* / CYP2J2* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000052520	37
Cyp2j11 / cytochrome P450, family 2, subfamily j, polypeptide 11 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000066097	37
Cyp2j13 / cytochrome P450, family 2, subfamily j, polypeptide 13 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000028571	36
Cyp2d22 / cytochrome P450, family 2, subfamily d, polypeptide 22 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...	ENSMUSG00000061740	36
Cyp2j8 / cytochrome P450, family 2, subfamily j, polypeptide 8 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000082932	36
Cyp2j12 / cytochrome P450, family 2, subfamily j, polypeptide 12 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000081225	35
Cyp2j7 / cytochrome P450, family 2, subfamily j, polypeptide 7 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*	ENSMUSG00000081362	35
P24456 / Cyp2d10 / Cytochrome P450 2D10 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...	ENSMUSG00000094806	34
P24457 / Cyp2d11 / Cytochrome P450 2D11 / CYP2D7* / CYP2D6* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/p...	ENSMUSG00000068085	33
Cyp2d9 / P11714 / Cytochrome P450 2D9 / CYP2D6* / P10635* / CYP2D7* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)*	ENSMUSG00000068086	33
Cyp2d34 / cytochrome P450, family 2, subfamily d, polypeptide 34 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...	ENSMUSG00000094559	33
Cyp2d12 / cytochrome P450, family 2, subfamily d, polypeptide 12 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...	ENSMUSG00000096852	33
Cyp2w1 / E9Q816 / Cytochrome P450 2W1 / Q8TAV3* / cytochrome P450 family 2 subfamily W member 1*	ENSMUSG00000029541	28
Cyp2d40 / cytochrome P450, family 2, subfamily d, polypeptide 40 / CYP2D6* / CYP2D7* / P10635* / A0A087X1C5* / cytochrome P450 family 2 subfamily D member 6* / cytochrome P450 family 2 subf...	ENSMUSG00000068083	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR001128	Cytochrome P450
IPR002401	Cytochrome P450, E-class, group I
IPR008069	Cytochrome P450, E-class, group I, CYP2D-like
IPR017972	Cytochrome P450, conserved site
IPR036396	Cytochrome P450 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0005789	endoplasmic reticulum membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031090	organelle membrane	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0004497	monooxygenase activity	IEA
molecular_function	GO:0005506	iron ion binding	IEA
molecular_function	GO:0008395	steroid hydroxylase activity	IBA
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
molecular_function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA
molecular_function	GO:0020037	heme binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0070330	aromatase activity	IEA

Pathways (from Reactome)

Pathway description

Miscellaneous substrates

Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ Genetic Background: C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr