ENSMUSG00000028033


Mus musculus

Features
Gene ID: ENSMUSG00000028033
  
Biological name :Kcnq5
  
Synonyms : Kcnq5 / Potassium voltage-gated channel subfamily KQT member 5 / Q9JK45
  
Possible biological names infered from orthology : potassium voltage-gated channel subfamily Q member 5 / Q9NR82
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: A4
Gene start: 21398403
Gene end: 21961942
  
Corresponding Affymetrix probe sets: 10353460 (MoGene1.0st)   1427426_at (Mouse Genome 430 2.0 Array)   1441071_at (Mouse Genome 430 2.0 Array)   1457587_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110955
Ensembl peptide - ENSMUSP00000134166
Ensembl peptide - ENSMUSP00000134389
Ensembl peptide - ENSMUSP00000029667
Ensembl peptide - ENSMUSP00000134076
NCBI entrez gene - 226922     See in Manteia.
MGI - MGI:1924937
RefSeq - XM_011238368
RefSeq - NM_001160139
RefSeq - NM_001310477
RefSeq - NM_023872
RefSeq Peptide - NP_076361
RefSeq Peptide - NP_001153611
RefSeq Peptide - NP_001297406
swissprot - G3UZ84
swissprot - G3UYG5
swissprot - G3UYP4
swissprot - Q9JK45
swissprot - E9Q9F1
Ensembl - ENSMUSG00000028033
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnq5aENSDARG00000069954Danio rerio
 kcnq5bENSDARG00000069953Danio rerio
 KCNQ5ENSGALG00000037249Gallus gallus
 KCNQ5ENSG00000185760Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnq2 / potassium voltage-gated channel subfamily KQT member 2 isoform 13 / O43526* / potassium voltage-gated channel subfamily Q member 2*ENSMUSG0000001634642
Kcnq4 / Q9JK97 / Potassium voltage-gated channel subfamily KQT member 4 / P56696* / potassium voltage-gated channel subfamily Q member 4*ENSMUSG0000002863142
Kcnq3 / Q8K3F6 / Potassium voltage-gated channel subfamily KQT member 3 / O43525* / potassium voltage-gated channel subfamily Q member 3*ENSMUSG0000005625838
Kcnq1 / P97414 / Potassium voltage-gated channel subfamily KQT member 1 / P51787* / potassium voltage-gated channel subfamily Q member 1*ENSMUSG0000000954527


Protein motifs (from Interpro)
Interpro ID Name
 IPR003937  Potassium channel, voltage dependent, KCNQ
 IPR005821  Ion transport domain
 IPR013821  Potassium channel, voltage dependent, KCNQ, C-terminal
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030118 clathrin coat IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003412 abnormal afterhyperpolarization "anomaly in the currents that follow an action potential and influence firing frequency and neuronal integration" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94941]
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Allelic Composition: Mad2l1tm1Sorg/Mad2l1+,Usp44tm1.2Pjgl/Usp44tm1.2Pjgl
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S7/SvEvBrd

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Mad2l1tm1Sorg/Mad2l1+,Usp44tm1.2Pjgl/Usp44tm1.2Pjgl
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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