ENSMUSG00000028743


Mus musculus

Features
Gene ID: ENSMUSG00000028743
  
Biological name :Akr7a5
  
Synonyms : Aflatoxin B1 aldehyde reductase member 2 / Akr7a5 / Q8CG76
  
Possible biological names infered from orthology : AKR7A2 / aldo-keto reductase family 7 member A2 / O43488
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 139310744
Gene end: 139318426
  
Corresponding Affymetrix probe sets: 10509635 (MoGene1.0st)   1417294_at (Mouse Genome 430 2.0 Array)   1438315_x_at (Mouse Genome 430 2.0 Array)   1458300_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073459
NCBI entrez gene - 110198     See in Manteia.
MGI - MGI:107796
RefSeq - NM_025337
RefSeq Peptide - NP_079613
swissprot - Q8CG76
Ensembl - ENSMUSG00000028743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr7a3ENSDARG00000016649Danio rerio
 ENSGALG00000004005Gallus gallus
 AKR7A2ENSG00000053371Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnab1 / P63143 / Voltage-gated potassium channel subunit beta-1 / Q14722* / potassium voltage-gated channel subfamily A member regulatory beta subunit 1*ENSMUSG0000002782725
Kcnab2 / P62482 / Voltage-gated potassium channel subunit beta-2 / Q13303* / potassium voltage-gated channel subfamily A regulatory beta subunit 2*ENSMUSG0000002893125
Kcnab3 / potassium voltage-gated channel subfamily A regulatory beta subunit 3 / O43448*ENSMUSG0000001847023


Protein motifs (from Interpro)
Interpro ID Name
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0044597 daunorubicin metabolic process IEA
 biological_processGO:0044598 doxorubicin metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019119 phenanthrene-9,10-epoxide hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028743 Q8CG76 / Akr7a5 / Aflatoxin B1 aldehyde reductase member 2 / AKR7A2* / O43488* / aldo-keto reductase family 7 member A2*  / complex






 

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