ENSMUSG00000030109


Mus musculus

Features
Gene ID: ENSMUSG00000030109
  
Biological name :Slc6a12
  
Synonyms : Slc6a12 / solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
  
Possible biological names infered from orthology : P48065 / solute carrier family 6 member 12
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F1
Gene start: 121343076
Gene end: 121365775
  
Corresponding Affymetrix probe sets: 10541333 (MoGene1.0st)   1449382_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128217
Ensembl peptide - ENSMUSP00000127779
Ensembl peptide - ENSMUSP00000129389
Ensembl peptide - ENSMUSP00000130715
Ensembl peptide - ENSMUSP00000032200
Ensembl peptide - ENSMUSP00000126708
Ensembl peptide - ENSMUSP00000126937
NCBI entrez gene - 14411     See in Manteia.
MGI - MGI:95628
RefSeq - XM_006505536
RefSeq - NM_133661
RefSeq - XM_006505533
RefSeq - XM_006505534
RefSeq - XM_006505535
RefSeq Peptide - NP_598422
RefSeq Peptide - NP_001334362
swissprot - Q8VCS9
swissprot - E9Q5U8
swissprot - F6SJH4
swissprot - F7AYZ6
swissprot - E9PXG1
swissprot - G5E8Z4
swissprot - E9PW98
Ensembl - ENSMUSG00000030109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC6A12ENSGALG00000019290Gallus gallus
 P48065ENSG00000111181Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P31649 / Slc6a13 / Sodium- and chloride-dependent GABA transporter 2 / Q9NSD5* / solute carrier family 6 member 13*ENSMUSG0000003010864
P31650 / Slc6a11 / Sodium- and chloride-dependent GABA transporter 3 / P48066* / solute carrier family 6 member 11*ENSMUSG0000003030763
O35316 / Slc6a6 / solute carrier family 6 (neurotransmitter transporter, taurine), member 6 / P31641* / solute carrier family 6 member 6*ENSMUSG0000003009657
Q8VBW1 / Slc6a8 / solute carrier family 6 (neurotransmitter transporter, creatine), member 8 / P48029* / solute carrier family 6 member 8*ENSMUSG0000001955850
P31648 / Slc6a1 / Sodium- and chloride-dependent GABA transporter 1 / P30531* / solute carrier family 6 member 1*ENSMUSG0000003031047
Slc6a5 / solute carrier family 6 (neurotransmitter transporter, glycine), member 5 / Q9Y345* / solute carrier family 6 member 5*ENSMUSG0000003972842
Q6PGE7 / Slc6a7 / Sodium-dependent proline transporter / Q99884* / solute carrier family 6 member 7*ENSMUSG0000005202642
Q61327 / Slc6a3 / Sodium-dependent dopamine transporter / Q01959* / solute carrier family 6 member 3*ENSMUSG0000002160940
O55192 / Slc6a2 / solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 / P23975* / solute carrier family 6 member 2*ENSMUSG0000005536840
Q60857 / Slc6a4 / Sodium-dependent serotonin transporter / P31645* / solute carrier family 6 member 4*ENSMUSG0000002083839
P28571 / Slc6a9 / Sodium- and chloride-dependent glycine transporter 1 / P48067* / solute carrier family 6 member 9*ENSMUSG0000002854238
Q9JMA9 / Slc6a14 / Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) / Q9UN76* / solute carrier family 6 member 14*ENSMUSG0000003108938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002983  Sodium:neurotransmitter symporter, betaine
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0015812 gamma-aminobutyric acid transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0005332 gamma-aminobutyric acid:sodium symporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters
Creatine metabolism
Reuptake of GABA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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