ENSMUSG00000030134


Mus musculus

Features
Gene ID: ENSMUSG00000030134
  
Biological name :Rasgef1a
  
Synonyms : Rasgef1a / RasGEF domain family, member 1A
  
Possible biological names infered from orthology : Q8N9B8
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F1
Gene start: 118011438
Gene end: 118091546
  
Corresponding Affymetrix probe sets: 10541114 (MoGene1.0st)   1429316_at (Mouse Genome 430 2.0 Array)   1435218_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145077
Ensembl peptide - ENSMUSP00000145214
Ensembl peptide - ENSMUSP00000132244
NCBI entrez gene - 70727     See in Manteia.
MGI - MGI:1917977
RefSeq - XM_017321738
RefSeq - NM_027526
RefSeq - XM_006506595
RefSeq - XM_006506596
RefSeq - XM_006506597
RefSeq - XM_017321737
RefSeq - NM_001316749
RefSeq Peptide - NP_081802
RefSeq Peptide - NP_001303678
swissprot - A6H650
swissprot - A0A0N4SVR5
swissprot - A0A0N4SVF2
Ensembl - ENSMUSG00000030134
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RASGEF1AENSGALG00000002525Gallus gallus
 Q8N9B8ENSG00000198915Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8JZL7 / Rasgef1b / Ras-GEF domain-containing family member 1B / Q0VAM2* / RasGEF domain family member 1B*ENSMUSG0000008980958
Q9D300 / Rasgef1c / Ras-GEF domain-containing family member 1C / Q8N431* / RasGEF domain family member 1C*ENSMUSG0000002037451
Q8CHG7 / Rapgef2 / Rap guanine nucleotide exchange factor 2 / Q9Y4G8*ENSMUSG0000006223224
Rapgef6 / Rap guanine nucleotide exchange factor (GEF) 6 / Q8TEU7* / AC008695.1* / Rap guanine nucleotide exchange factor 6*ENSMUSG0000003753323
Q8C0Q9 / Rapgef5 / Rap guanine nucleotide exchange factor 5 / Q92565*ENSMUSG0000004199221
Q9EQZ6 / Rapgef4 / Rap guanine nucleotide exchange factor (GEF) 4 / Q8WZA2* / Rap guanine nucleotide exchange factor 4*ENSMUSG0000004904421
Q8VCC8 / Rapgef3 / Mus musculus Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), transcript variant 4, mRNA. / O95398* / Rap guanine nucleotide exchange factor 3*ENSMUSG0000002246920
Q9Z1S3 / Rasgrp1 / RAS guanyl releasing protein 1 / O95267*ENSMUSG0000002734718
Q9QUG9 / Rasgrp2 / RAS, guanyl releasing protein 2 / Q7LDG7*ENSMUSG0000003294617
Rasgrp3 / RAS, guanyl releasing protein 3 / Q8IV61*ENSMUSG0000007104217
Q8BTM9 / Rasgrp4 / RAS guanyl releasing protein 4 / Q8TDF6*ENSMUSG0000003058916
Q68EF8 / Rapgefl1 / Rap guanine nucleotide exchange factor-like 1 / Q9UHV5*ENSMUSG0000003802016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr