ENSMUSG00000030653


Mus musculus

Features
Gene ID: ENSMUSG00000030653
  
Biological name :Gm45837
  
Synonyms : cGMP-dependent 3,5-cyclic phosphodiesterase isoform PDE2A1 / Gm45837
  
Possible biological names infered from orthology : O00408 / PDE2A / phosphodiesterase 2A
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E2
Gene start: 101410886
Gene end: 101512819
  
Corresponding Affymetrix probe sets: 10555510 (MoGene1.0st)   1447707_s_at (Mouse Genome 430 2.0 Array)   1447708_x_at (Mouse Genome 430 2.0 Array)   1452202_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081956
NCBI entrez gene - 207728     See in Manteia.
MGI - MGI:5804952
RefSeq - XM_011241718
RefSeq - NM_001243757
RefSeq - XM_006507526
RefSeq - XM_006507527
RefSeq - XM_006507525
RefSeq Peptide - NP_001230686
swissprot - F7D3W5
Ensembl - ENSMUSG00000030653
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079080.1ENSDARG00000079064Danio rerio
 PDE2AENSG00000186642Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pde2a / phosphodiesterase 2A, cGMP-stimulated / O00408* / phosphodiesterase 2A*ENSMUSG0000011019594
P0C1Q2 / Pde11a / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A / Q9HCR9* / phosphodiesterase 11A*ENSMUSG0000007527025
Pde10a / Q8CA95 / phosphodiesterase 10A / Q9Y233*ENSMUSG0000002386823
Pde6b / P23440 / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide / P35913* / phosphodiesterase 6B*ENSMUSG0000002949123
Pde5a / Q8CG03 / cGMP-specific 3,5-cyclic phosphodiesterase / O76074* / phosphodiesterase 5A*ENSMUSG0000005396523
Pde6a / phosphodiesterase 6A / P16499*ENSMUSG0000002457522
Pde6c / Q91ZQ1 / Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / phosphodiesterase 6C*ENSMUSG0000002499221
Pde3b / phosphodiesterase 3B / Q13370*ENSMUSG0000003067114
Pde9a / O70628 / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A / O76083* / phosphodiesterase 9A*ENSMUSG0000004111913
Pde3a / Q9Z0X4 / phosphodiesterase 3A, cGMP inhibited / Q14432* / phosphodiesterase 3A*ENSMUSG0000004174113


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003018  GAF domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR029016  GAF-like domain superfamily
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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