ENSMUSG00000053965
Mus musculus phosphodiesterase regulation activity Pde5a nucleotide domain cgmp -cyclic process binding catalytic metabolic cardiac muscle superfamily protein hydrolase gaf hd pdease conserved site gaf-like signal transduction hypertrophy obsolete t cell proliferation map
Features Gene ID: ENSMUSG00000053965 Biological name :Pde5a Synonyms : cGMP-specific 3,5-cyclic phosphodiesterase / Pde5a / Q8CG03 Possible biological names infered from orthology : O76074 / phosphodiesterase 5A Species: Mus musculus Chr. number: 3 Strand: 1 Band: G1 Gene start: 122728947 Gene end: 122859374 Corresponding Affymetrix probe sets: 10495794 (MoGene1.0st) 1455970_at (Mouse Genome 430 2.0 Array) 1458341_x_at (Mouse Genome 430 2.0 Array) 1460118_at (Mouse Genome 430 2.0 Array) Cross references: Ensembl peptide - ENSMUSP00000143042 Ensembl peptide - ENSMUSP00000069011 NCBI entrez gene - 242202
See in Manteia .
MGI - MGI:2651499 RefSeq - NM_153422 RefSeq - XM_006501481 RefSeq Peptide - NP_700471 swissprot - A0A0G2JF67 swissprot - Q8CG03 Ensembl - ENSMUSG00000053965
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) P0C1Q2 / Pde11a / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A / Q9HCR9* / phosphodiesterase 11A* ENSMUSG00000075270 40 Pde6b / P23440 / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide / P35913* / phosphodiesterase 6B* ENSMUSG00000029491 30 Pde6c / Q91ZQ1 / Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160* / phosphodiesterase 6C* ENSMUSG00000024992 29 Pde6a / phosphodiesterase 6A / P16499* ENSMUSG00000024575 28 Pde10a / Q8CA95 / phosphodiesterase 10A / Q9Y233* ENSMUSG00000023868 27 Gm45837 / cGMP-dependent 3,5-cyclic phosphodiesterase isoform PDE2A1 / PDE2A* / O00408* / phosphodiesterase 2A* ENSMUSG00000030653 25 Pde2a / phosphodiesterase 2A, cGMP-stimulated / O00408* / phosphodiesterase 2A* ENSMUSG00000110195 25 Pde3b / phosphodiesterase 3B / Q13370* ENSMUSG00000030671 14 Pde9a / O70628 / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A / O76083* / phosphodiesterase 9A* ENSMUSG00000041119 14 Pde3a / Q9Z0X4 / phosphodiesterase 3A, cGMP inhibited / Q14432* / phosphodiesterase 3A* ENSMUSG00000041741 14
Protein motifs (from Interpro ) IPR002073 3"5"-cyclic nucleotide phosphodiesterase, catalytic domain IPR003018 GAF domain IPR003607 HD/PDEase domain IPR023088 3"5"-cyclic nucleotide phosphodiesterase IPR023174 3"5"-cyclic nucleotide phosphodiesterase, conserved site IPR029016 GAF-like domain superfamily IPR036971 3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
Gene Ontology (GO ) cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell communication cellular response to stimulus system process cell activation cell adhesion leukocyte proliferation nitrogen compound metabolic process cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process small molecule metabolic process biosynthetic process catabolic process anatomical structure development cellular developmental process multicellular organism reproduction cell comcell communication cellularcellular response to stimulus system psystem process cell actcell activation cell adhcell adhesion leukocytleukocyte proliferation nitrogennitrogen compound metabolic process cellularcellular metabolic process primary primary metabolic process regulatiregulation of molecular function organic organic substance metabolic process small mosmall molecule metabolic process biosynthbiosynthetic process catabolicatabolic process anatomicanatomical structure development cellularcellular developmental process multicelmulticellular organism reproduction organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding hydrolase activity protein binding ion binding carbohydrate derivative binding organic cyclic compoorganic cyclic compound binding heterocyclic compounheterocyclic compound binding small molecule bindismall molecule binding hydrolase activityhydrolase activity protein bindingprotein binding ion bindingion binding carbohydrate derivatcarbohydrate derivative binding
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO )
No match
Interacting proteins (from Reactome )No match
0 s.