ENSDARG00000051915


Danio rerio

Features
Gene ID: ENSDARG00000051915
  
Biological name :pde5ab
  
Synonyms : pde5ab / phosphodiesterase 5A, cGMP-specific, b
  
Possible biological names infered from orthology : cGMP-specific 3,5-cyclic phosphodiesterase / O76074 / PDE5A / phosphodiesterase 5A / Q8CG03
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 57539146
Gene end: 57619470
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000068115
Ensembl peptide - ENSDARP00000114140
NCBI entrez gene - 553270     See in Manteia.
RefSeq - NM_001123260
RefSeq Peptide - NP_001116732
swissprot - B0S7D6
swissprot - A0A1Q2XE08
swissprot - F1QZ12
ZFIN ID - ZDB-GENE-060824-4
Ensembl - ENSDARG00000051915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE5AENSGALG00000011982Gallus gallus
 PDE5AENSG00000138735Homo sapiens
 Pde5aENSMUSG00000053965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pde11al / phosphodiesterase 11a, likeENSDARG0000000615138
pde11a / phosphodiesterase 11a / P0C1Q2* / Q9HCR9* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSDARG0000006373237
pde6a / phosphodiesterase 6A, cGMP-specific, rod, alpha / P16499* / phosphodiesterase 6A*ENSDARG0000000038028
pde6b / phosphodiesterase 6B, cGMP-specific, rod, beta / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSDARG0000001167128
pde6c / phosphodiesterase 6C, cGMP-specific, cone, alpha prime / P51160* / Q91ZQ1* / phosphodiesterase 6C* / Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha *ENSDARG0000010039728
pde10a / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSDARG0000000344926
pde3a / phosphodiesterase 3A, cGMP-inhibited / Q14432* / Q9Z0X4* / phosphodiesterase 3A*ENSDARG0000000422715
PDE3B / si:ch211-79e4.4 / Q13370* / phosphodiesterase 3B*ENSDARG0000006219015
pde9a / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSDARG0000006028013
pde9al / phosphodiesterase 9A like / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000007665013
FQ378016.1 / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000010893913
pde5aa / phosphodiesterase 5A, cGMP-specific, aENSDARG0000005680612
si:dkey-219c10.4ENSDARG0000007592911
CABZ01079080.1 / PDE2A* / O00408* / phosphodiesterase 2A*ENSDARG000000790645


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003018  GAF domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR029016  GAF-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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