ENSDARG00000011671


Danio rerio

Features
Gene ID: ENSDARG00000011671
  
Biological name :pde6b
  
Synonyms : pde6b / phosphodiesterase 6B, cGMP-specific, rod, beta
  
Possible biological names infered from orthology : P23440 / P35913 / phosphodiesterase 6B / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 20356458
Gene end: 20376607
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123023
NCBI entrez gene - 559332     See in Manteia.
RefSeq - XM_679910
swissprot - E7F5I9
ZFIN ID - ZDB-GENE-090421-2
Ensembl - ENSDARG00000011671
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE6BENSGALG00000015373Gallus gallus
 PDE6BENSG00000133256Homo sapiens
 Pde6bENSMUSG00000029491Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pde6a / phosphodiesterase 6A, cGMP-specific, rod, alpha / P16499* / phosphodiesterase 6A*ENSDARG0000000038073
pde6c / phosphodiesterase 6C, cGMP-specific, cone, alpha prime / P51160* / Q91ZQ1* / phosphodiesterase 6C* / Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha *ENSDARG0000010039762
pde11al / phosphodiesterase 11a, likeENSDARG0000000615130
pde11a / phosphodiesterase 11a / P0C1Q2* / Q9HCR9* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSDARG0000006373230
pde5ab / phosphodiesterase 5A, cGMP-specific, b / PDE5A* / Q8CG03* / O76074* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase *ENSDARG0000005191528
pde10a / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSDARG0000000344923
pde3a / phosphodiesterase 3A, cGMP-inhibited / Q14432* / Q9Z0X4* / phosphodiesterase 3A*ENSDARG0000000422718
PDE3B / si:ch211-79e4.4 / Q13370* / phosphodiesterase 3B*ENSDARG0000006219016
pde9al / phosphodiesterase 9A like / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000007665015
FQ378016.1 / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000010893915
pde9a / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSDARG0000006028014
si:dkey-219c10.4ENSDARG0000007592911
pde5aa / phosphodiesterase 5A, cGMP-specific, aENSDARG000000568067
CABZ01079080.1 / PDE2A* / O00408* / phosphodiesterase 2A*ENSDARG000000790644


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003018  GAF domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR029016  GAF-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
Ca2+ pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009127 photoreceptor cell photoreceptor cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000000380 pde6a / phosphodiesterase 6A, cGMP-specific, rod, alpha / P16499* / phosphodiesterase 6A*  / complex
 ENSDARG00000044199 gnat1 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 / P20612* / P11488* / G protein subunit alpha transducin 1* / guanine nucleotide binding pro...  / complex
 ENSDARG00000042529 gnat2 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 / P50149* / P19087* / G protein subunit alpha transducin 2* / guanine nucleotide binding pro...  / complex
 ENSDARG00000101984 pde6gb / phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b / PDE6G* / P18545* / phosphodiesterase 6G*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr