ENSMUSG00000030751


Mus musculus
proteasomePsma1complexactivitysubunitprocessproteinalpha-subunitn-terminalalphaproteolysiscataboliccorebindingendopeptidasedomainbetaalpha-typenucleophileaminohydrolasesimmuneregulationinflammatoryresponseantigenicstimulusubiquitin-dependentinvolvedcellularnucleusnucleoplasm

Features
Gene ID: ENSMUSG00000030751
  
Biological name :Psma1
  
Synonyms : proteasome (prosome, macropain) subunit, alpha type 1 / Psma1 / Q9R1P4
  
Possible biological names infered from orthology : AC018523.2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F1
Gene start: 114264606
Gene end: 114276118
  
Corresponding Affymetrix probe sets: 10567072 (MoGene1.0st)   10338120 (MoGene1.0st)   10339471 (MoGene1.0st)   10339523 (MoGene1.0st)   10340822 (MoGene1.0st)   10341145 (MoGene1.0st)   10341761 (MoGene1.0st)   10341880 (MoGene1.0st)   10341921 (MoGene1.0st)   10342779 (MoGene1.0st)   10342997 (MoGene1.0st)   10343233 (MoGene1.0st)   10343968 (MoGene1.0st)   10338071 (MoGene1.0st)   10338473 (MoGene1.0st)   10338636 (MoGene1.0st)   10338963 (MoGene1.0st)   10338968 (MoGene1.0st)   10339324 (MoGene1.0st)   10339949 (MoGene1.0st)   10340335 (MoGene1.0st)   10340974 (MoGene1.0st)   10341203 (MoGene1.0st)   10341795 (MoGene1.0st)   10342081 (MoGene1.0st)   10342147 (MoGene1.0st)   10342727 (MoGene1.0st)   10343203 (MoGene1.0st)   10343578 (MoGene1.0st)   10344586 (MoGene1.0st)   1415695_at (Mouse Genome 430 2.0 Array)   1436769_at (Mouse Genome 430 2.0 Array)   1436770_x_at (Mouse Genome 430 2.0 Array)   1458292_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147815
Ensembl peptide - ENSMUSP00000033008
NCBI entrez gene - 26440     See in Manteia.
MGI - MGI:1347005
RefSeq - NM_011965
RefSeq Peptide - NP_036095
swissprot - A0A1B0GS70
swissprot - Q3TS44
swissprot - Q9R1P4
Ensembl - ENSMUSG00000030751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psma1ENSDARG00000101560Danio rerio
 PSMA1ENSGALG00000006022Gallus gallus
 AC018523.2ENSG00000256206Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000426  Proteasome alpha-subunit, N-terminal domain
 IPR001353  Proteasome, subunit alpha/beta
 IPR023332  Proteasome alpha-type subunit
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR035144  Proteasome subunit alpha 1


Gene Ontology (GO)
response to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stressimmune responseresponse to external stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular metabolic processresponse to stresresponse to stressimmune responseimmune responseresponse to exterresponse to external stimulusnitrogen compoundnitrogen compound metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processcatabolic processcatabolic processcellular metabolicellular metabolic process
lipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindingcarbohydrate derivative bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindinglipid bindinglipid bindingcarbohydrate derivative bindcarbohydrate derivative bindingcatalytic activity, acting ocatalytic activity, acting on a proteinhydrolase activityhydrolase activityprotein bindingprotein binding
cellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellcellprotein-containing complexprotein-containing complexorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002862 negative regulation of inflammatory response to antigenic stimulus TAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005839 proteasome core complex IEA
 cellular_componentGO:0019773 proteasome core complex, alpha-subunit complex IEA
 molecular_functionGO:0001530 lipopolysaccharide binding IDA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004298 threonine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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