ENSMUSG00000032482


Mus musculus

Features
Gene ID: ENSMUSG00000032482
  
Biological name :Cspg5
  
Synonyms : Chondroitin sulfate proteoglycan 5 / Cspg5 / Q71M36
  
Possible biological names infered from orthology : O95196
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F2
Gene start: 110243783
Gene end: 110262576
  
Corresponding Affymetrix probe sets: 10589494 (MoGene1.0st)   1450713_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035058
Ensembl peptide - ENSMUSP00000142845
Ensembl peptide - ENSMUSP00000143005
Ensembl peptide - ENSMUSP00000143164
NCBI entrez gene - 29873     See in Manteia.
MGI - MGI:1352747
RefSeq - NM_001166273
RefSeq - NM_013884
RefSeq Peptide - NP_001159745
RefSeq Peptide - NP_038912
swissprot - Q71M36
Ensembl - ENSMUSG00000032482
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cspg5aENSDARG00000069981Danio rerio
 cspg5bENSDARG00000099793Danio rerio
 CSPG5ENSGALG00000032184Gallus gallus
 CSPG5ENSG00000114646Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009505  Neural chondroitin sulphate proteoglycan cytoplasmic
 IPR010555  CSPG5, sulphate attachment domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane ISO


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0001475 reduced long term depression "less than the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science:ISBN 0-8385-8034-3]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0002206 abnormal CNS synaptic transmission "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0002910 abnormal excitatory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0002919 enhanced paired-pulse facilitation "increase in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to greater increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0002945 abnormal inhibitory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Mcm3aptm1Imku/Mcm3aptm1Imku,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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