ENSMUSG00000032661


Mus musculus

Features
Gene ID: ENSMUSG00000032661
  
Biological name :Oas3
  
Synonyms : 2-5-oligoadenylate synthase 3 / Oas3 / Q8VI93
  
Possible biological names infered from orthology : 2-5-oligoadenylate synthetase 3 / Q9Y6K5
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 120753098
Gene end: 120777661
  
Corresponding Affymetrix probe sets: 10533213 (MoGene1.0st)   1425374_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035588
Ensembl peptide - ENSMUSP00000125873
NCBI entrez gene - 246727     See in Manteia.
MGI - MGI:2180850
RefSeq - NM_145226
RefSeq Peptide - NP_660261
swissprot - F7CXR7
swissprot - Q8VI93
Ensembl - ENSMUSG00000032661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OAS3ENSG00000111331Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Oas2 / E9Q9A9 / Mus musculus 2-5 oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA. / P29728* / 2-5-oligoadenylate synthetase 2*ENSMUSG0000003269029
Oas1a / P11928 / 2-5-oligoadenylate synthase 1A / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005277616
Oas1g / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686116
Oas1f / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005376514
Oas1c / Q924S2 / Inactive 2-5 oligoadenylate synthetase 1C / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116613
Oas1h / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116813
Oasl2 / Q9Z2F2 / 2-5-oligoadenylate synthase-like protein 2 ENSMUSG0000002956113
Oas1d / Q8VI95 / Inactive 2-5-oligoadenylate synthase 1D / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000003262313
Oas1e / Mus musculus 2-5 oligoadenylate synthetase 1E (Oas1e), transcript variant 1, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686713
Oasl1 / Q8VI94 / 2-5-oligoadenylate synthase-like protein 1 / OASL* / Q15646* / 2-5-oligoadenylate synthetase like*ENSMUSG0000004182712
Oas1b / Mus musculus 2-5 oligoadenylate synthetase 1B (Oas1b), transcript variant 1, coding, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000002960510


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR006116  2-5-oligoadenylate synthetase, N-terminal
 IPR006117  2-5-oligoadenylate synthetase, conserved site
 IPR018952  2"-5"-oligoadenylate synthetase 1, domain 2/C-terminal
 IPR026774  2"-5"-oligoadenylate synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0045071 negative regulation of viral genome replication IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060700 regulation of ribonuclease activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001730 2"-5"-oligoadenylate synthetase activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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