ENSMUSG00000033196


Mus musculus

Features
Gene ID: ENSMUSG00000033196
  
Biological name :Myh2
  
Synonyms : Myh2 / myosin heavy chain 2
  
Possible biological names infered from orthology : Q9UKX2
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 67171027
Gene end: 67197517
  
Corresponding Affymetrix probe sets: 10377055 (MoGene1.0st)   1425153_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000018641
Ensembl peptide - ENSMUSP00000129544
NCBI entrez gene - 17882     See in Manteia.
MGI - MGI:1339710
RefSeq - NM_001039545
RefSeq Peptide - NP_001034634
swissprot - G3UW82
Ensembl - ENSMUSG00000033196
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079179.1ENSDARG00000110596Danio rerio
 myhbENSDARG00000001993Danio rerio
 myhz1.1ENSDARG00000102414Danio rerio
 myhz1.3ENSDARG00000067997Danio rerio
 myhz2ENSDARG00000012944Danio rerio
 zgc:66156ENSDARG00000112287Danio rerio
 MYH1AENSGALG00000037864Gallus gallus
 MYH1BENSGALG00000039977Gallus gallus
 MYH1CENSGALG00000032404Gallus gallus
 MYH1DENSGALG00000027323Gallus gallus
 MYH1FENSGALG00000042257Gallus gallus
 MYH1GENSGALG00000028612Gallus gallus
 MYH2ENSG00000125414Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myh1 / Q5SX40 / Myosin-1 / P12882* / myosin heavy chain 1*ENSMUSG0000005632895
Myh8 / P13542 / Myosin-8 / P13535* / myosin heavy chain 8*ENSMUSG0000005577593
Myh4 / Q5SX39 / Myosin-4 / Q9Y623* / myosin heavy chain 4*ENSMUSG0000005700393
Myh3 / P13541 / Myosin-3 / P11055* / myosin heavy chain 3*ENSMUSG0000002090885
Myh7 / Q91Z83 / Myosin-7 / P12883* / myosin heavy chain 7*ENSMUSG0000005309382
Myh13 / myosin heavy chain 13 / Q9UKX3*ENSMUSG0000006018082
Myh6 / Q02566 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P13533* / myosin heavy chain 6*ENSMUSG0000004075281
Myh7b / A2AQP0 / Myosin-7B / A7E2Y1* / myosin heavy chain 7B*ENSMUSG0000007465268
Myh15 / myosin heavy chain 15 / Q9Y2K3*ENSMUSG0000009200956
Myh11 / myosin heavy chain 11 / P35749*ENSMUSG0000001883041
Myh10 / Q61879 / Myosin-10 / P35580* / myosin heavy chain 10*ENSMUSG0000002090040
Myh9 / Q8VDD5 / myosin, heavy polypeptide 9, non-muscle / P35579* / myosin heavy chain 9*ENSMUSG0000002244340
Myh14 / Q6URW6 / Myosin-14 / Q7Z406* / myosin heavy chain 14*ENSMUSG0000003073937


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR004009  Myosin, N-terminal, SH3-like
 IPR008989  Myosin S1 fragment, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001778 plasma membrane repair IMP
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0014823 response to activity IDA
 biological_processGO:0070252 actin-mediated cell contraction IDA
 cellular_componentGO:0005794 Golgi apparatus IMP
 cellular_componentGO:0005826 actomyosin contractile ring IDA
 cellular_componentGO:0005859 muscle myosin complex ISO
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0031672 A band IDA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000062825 Actg1 / P63260 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processed / P63261* / actin gamma 1*  / complex
 ENSMUSG00000029580 Actb / P60710 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / POTEJ* / P60709* / P0CG39* / actin beta* / POTE ankyrin domain family member J*  / complex






 

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