ENSMUSG00000033543


Mus musculus

Features
Gene ID: ENSMUSG00000033543
  
Biological name :Gtf2a2
  
Synonyms : Gtf2a2 / Q80ZM7 / Transcription initiation factor IIA subunit 2
  
Possible biological names infered from orthology : general transcription factor IIA subunit 2 / P52657
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: D
Gene start: 70012550
Gene end: 70022866
  
Corresponding Affymetrix probe sets: 10586773 (MoGene1.0st)   1433528_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113109
Ensembl peptide - ENSMUSP00000121840
Ensembl peptide - ENSMUSP00000116962
Ensembl peptide - ENSMUSP00000113697
Ensembl peptide - ENSMUSP00000113501
Ensembl peptide - ENSMUSP00000112251
Ensembl peptide - ENSMUSP00000113061
NCBI entrez gene - 235459     See in Manteia.
MGI - MGI:1933289
RefSeq - XM_006511116
RefSeq - NM_001039519
RefSeq - NM_001282083
RefSeq - NM_001282084
RefSeq Peptide - NP_001269012
RefSeq Peptide - NP_001269013
RefSeq Peptide - NP_001034608
swissprot - Q05C74
swissprot - D3Z7C2
swissprot - D3Z793
swissprot - Q3TE88
swissprot - D3Z7S8
swissprot - Q80ZM7
swissprot - D6RIQ7
Ensembl - ENSMUSG00000033543
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2a2ENSDARG00000053685Danio rerio
 GTF2A2ENSGALG00000003793Gallus gallus
 GTF2A2ENSG00000140307Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003194  Transcription initiation factor IIA, gamma subunit
 IPR009083  Transcription factor IIA, helical
 IPR009088  Transcription factor IIA, beta-barrel
 IPR015871  Transcription initiation factor IIA, gamma subunit, C-terminal
 IPR015872  Transcription initiation factor IIA, gamma subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IBA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005672 transcription factor TFIIA complex IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IPI
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0017025 TBP-class protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase II Pre-transcription Events
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014767 Tbp / P29037 / TATA box binding protein / P20226*  / complex / reaction
 ENSMUSG00000024382 Ercc3 / P49135 / TFIIH basal transcription factor complex helicase XPB subunit / P19447* / ERCC excision repair 3, TFIIH core complex helicase subunit*  / reaction
 ENSMUSG00000020962 Gtf2a1 / Q99PM3 / Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA alpha chain Transcription initiation factor IIA beta chain / P52655* / general transcript...  / complex
 ENSMUSG00000109324 Prmt1 / Q9JIF0 / protein arginine N-methyltransferase 1 / Q99873* / protein arginine methyltransferase 1*  / complex / reaction
 ENSMUSG00000035451 Foxa1 / P35582 / Hepatocyte nuclear factor 3-alpha / P55317* / forkhead box A1*  / complex / reaction
 ENSMUSG00000019768 Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*  / complex / reaction
 ENSMUSG00000015619 Gata3 / P23772 / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA. / P23771* / GATA binding protein 3*  / complex / reaction
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / complex / reaction
 ENSMUSG00000022828 Gtf2e1 / Q9D0D5 / Mus musculusral transcription factor II E, polypeptide 1 (alpha subunit) (Gtf2e1), transcript variant 2, mRNA. / P29083* / general transcription factor IIE subunit 1*  / complex / reaction
 ENSMUSG00000028271 Gtf2b / P62915 / Transcription initiation factor IIB / Q00403* / general transcription factor IIB*  / complex / reaction
 ENSMUSG00000032185 Carm1 / Q9WVG6 / Histone-arginine methyltransferase CARM1 / Q86X55* / coactivator associated arginine methyltransferase 1*  / complex / reaction
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / complex / reaction
 ENSMUSG00000031585 Gtf2e2 / Q9D902 / ral transcription factor IIE subunit 2 / P29084* / general transcription factor IIE subunit 2*  / complex / reaction






 

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