ENSMUSG00000034557


Mus musculus

Features
Gene ID: ENSMUSG00000034557
  
Biological name :Zfyve9
  
Synonyms : Zfyve9 / zinc finger, FYVE domain containing 9
  
Possible biological names infered from orthology : O95405 / zinc finger FYVE-type containing 9
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C7
Gene start: 108637466
Gene end: 108780798
  
Corresponding Affymetrix probe sets: 10515028 (MoGene1.0st)   1440348_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102268
Ensembl peptide - ENSMUSP00000102269
Ensembl peptide - ENSMUSP00000039852
NCBI entrez gene - 230597     See in Manteia.
MGI - MGI:2652838
RefSeq - XM_017320143
RefSeq - NM_183300
RefSeq - XM_006502986
RefSeq - XM_006502987
RefSeq - XM_006502988
RefSeq - XM_006502989
RefSeq - NM_001347163
RefSeq Peptide - NP_899123
RefSeq Peptide - NP_001334092
swissprot - A8Y5G5
swissprot - A2A8R0
swissprot - A0S860
Ensembl - ENSMUSG00000034557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfyve9aENSDARG00000101903Danio rerio
 zfyve9bENSDARG00000100764Danio rerio
 ZFYVE9ENSGALG00000010613Gallus gallus
 O95405ENSG00000157077Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80U44 / Zfyve16 / zinc finger, FYVE domain containing 16 / Q7Z3T8* / zinc finger FYVE-type containing 16*ENSMUSG0000002170636
Q9Z1T6 / Pikfyve / phosphoinositide kinase, FYVE type zinc finger containing / Q9Y2I7*ENSMUSG0000002594913
Q6ZPK7 / Zfyve28 / zinc finger, FYVE domain containing 28 / Q9HCC9* / zinc finger FYVE-type containing 28*ENSMUSG000000372248
Q8VCM3 / Zfyve21 / zinc finger, FYVE domain containing 21 / Q9BQ24* / zinc finger FYVE-type containing 21*ENSMUSG000000212865


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR022557  Domain of unknown function DUF3480
 IPR024608  Smad anchor for receptor activation, Smad-binding domain
 IPR035438  Zinc finger FYVE domain containing protein, SARA/endofin
 IPR037145  Smad anchor for receptor activation, Smad-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0007183 SMAD protein complex assembly ISO
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0031901 early endosome membrane ISO
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005545 1-phosphatidylinositol binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0046332 SMAD binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TGF-beta receptor signaling activates SMADs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002603 Tgfb1 / P04202 / transforming growth factor, beta 1 / P01137*  / complex / reaction
 ENSMUSG00000007613 Q64729 / Tgfbr1 / transforming growth factor, beta receptor I / P36897* / transforming growth factor beta receptor 1*  / complex / reaction
 ENSMUSG00000024563 Smad2 / Q62432 / Mothers against decapentaplegic homolog 2 / Q15796* / SMAD family member 2*  / reaction
 ENSMUSG00000032440 Q62312 / Tgfbr2 / transforming growth factor, beta receptor II / P37173* / transforming growth factor beta receptor 2*  / complex / reaction
 ENSMUSG00000032402 Smad3 / Q8BUN5 / Mothers against decapentaplegic homolog 3 / P84022* / SMAD family member 3*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr