ENSMUSG00000021706


Mus musculus

Features
Gene ID: ENSMUSG00000021706
  
Biological name :Zfyve16
  
Synonyms : Q80U44 / Zfyve16 / zinc finger, FYVE domain containing 16
  
Possible biological names infered from orthology : Q7Z3T8 / zinc finger FYVE-type containing 16
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: C3
Gene start: 92487108
Gene end: 92530868
  
Corresponding Affymetrix probe sets: 10411059 (MoGene1.0st)   1447947_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022217
NCBI entrez gene - 218441     See in Manteia.
MGI - MGI:2145181
RefSeq - XM_006517582
RefSeq - NM_173392
RefSeq - XM_006517580
RefSeq Peptide - NP_775568
swissprot - Q80U44
Ensembl - ENSMUSG00000021706
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfyve16ENSDARG00000075747Danio rerio
 ZFYVE16ENSGALG00000015576Gallus gallus
 Q7Z3T8ENSG00000039319Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfyve9 / zinc finger, FYVE domain containing 9 / O95405* / zinc finger FYVE-type containing 9*ENSMUSG0000003455733
Q9Z1T6 / Pikfyve / phosphoinositide kinase, FYVE type zinc finger containing / Q9Y2I7*ENSMUSG0000002594913
Q6ZPK7 / Zfyve28 / zinc finger, FYVE domain containing 28 / Q9HCC9* / zinc finger FYVE-type containing 28*ENSMUSG000000372249
Q8VCM3 / Zfyve21 / zinc finger, FYVE domain containing 21 / Q9BQ24* / zinc finger FYVE-type containing 21*ENSMUSG000000212865


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017165  Zinc finger FYVE domain-containing protein, endofin
 IPR017455  Zinc finger, FYVE-related
 IPR022557  Domain of unknown function DUF3480
 IPR035438  Zinc finger FYVE domain containing protein, SARA/endofin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006622 protein targeting to lysosome IEA
 biological_processGO:0016197 endosomal transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005545 1-phosphatidylinositol binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by BMP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000061393 Acvr2b / P27040 / Activin receptor type-2B / Q13705* / activin A receptor type 2B*  / complex / reaction
 ENSMUSG00000052430 Bmpr1b / P36898 / Mus musculus bone morphotic protein receptor, type 1B (Bmpr1b), transcript variant 6, mRNA. / O00238* / bone morphogenetic protein receptor type 1B*  / complex / reaction
 ENSMUSG00000052155 Acvr2a / P27038 / Activin receptor type-2A / P27037* / activin A receptor type 2A*  / complex / reaction
 ENSMUSG00000021796 Bmpr1a / P36895 / Bone morphotic protein receptor type-1A / P36894* / bone morphogenetic protein receptor type 1A*  / complex / reaction
 ENSMUSG00000067336 Bmpr2 / O35607 / Bone morphotic protein receptor type-2 / Q13873* / bone morphogenetic protein receptor type 2*  / complex / reaction
 ENSMUSG00000027358 Bmp2 / P21274 / Bone morphotic protein 2 / P12643* / bone morphogenetic protein 2*  / complex / reaction
 ENSMUSG00000027796 Smad9 / Q9JIW5 / Mothers against decapentaplegic homolog 9 / O15198* / SMAD family member 9*  / complex / reaction
 ENSMUSG00000031681 Smad1 / P70340 / SMAD family member 1 / Q15797*  / complex / reaction
 ENSMUSG00000021540 Smad5 / P97454 / Mothers against decapentaplegic homolog 5 / Q99717* / SMAD family member 5*  / complex / reaction






 

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