ENSMUSG00000034931


Mus musculus

Features
Gene ID: ENSMUSG00000034931
  
Biological name :Dhx8
  
Synonyms : A2A4P0 / ATP-dependent RNA helicase DHX8 / Dhx8
  
Possible biological names infered from orthology : DEAH-box helicase 8 / Q14562
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 101732919
Gene end: 101767358
  
Corresponding Affymetrix probe sets: 10381477 (MoGene1.0st)   1426629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037251
Ensembl peptide - ENSMUSP00000119430
NCBI entrez gene - 217207     See in Manteia.
MGI - MGI:1306823
RefSeq - NM_144831
RefSeq Peptide - NP_659080
swissprot - A2A4P0
swissprot - A2A4N9
Ensembl - ENSMUSG00000034931
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx8ENSDARG00000054707Danio rerio
 DHX8ENSGALG00000032305Gallus gallus
 DHX8ENSG00000067596Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dhx38 / DEAH-box helicase 38 / Q92620*ENSMUSG0000003799337
Dhx16 / DEAH-box helicase 16 / O60231*ENSMUSG0000002442236
Dhx15 / O35286 / Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 / O43143* / DEAH-box helicase 15*ENSMUSG0000002916930
Dhx35 / probable ATP-dependent RNA helicase DHX35 isoform b / Q9H5Z1* / DEAH-box helicase 35*ENSMUSG0000002765525
Dhx33 / Q80VY9 / Putative ATP-dependent RNA helicase DHX33 / Q9H6R0* / DEAH-box helicase 33*ENSMUSG0000004062025
Dhx40 / Q6PE54 / Probable ATP-dependent RNA helicase DHX40 / Q8IX18* / DEAH-box helicase 40*ENSMUSG0000001842524
Dhx34 / DExH-box helicase 34 / Q14147*ENSMUSG0000000601921
Cltc / Q68FD5 / Mus musculus clathrin, heavy polypeptide (Hc) (Cltc), transcript variant 1, mRNA.ENSMUSG0000004712613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR003029  S1 domain
 IPR007502  Helicase-associated domain
 IPR011709  Domain of unknown function DUF1605
 IPR012340  Nucleic acid-binding, OB-fold
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR022967  RNA-binding domain, S1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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