ENSMUSG00000047126


Mus musculus

Features
Gene ID: ENSMUSG00000047126
  
Biological name :Cltc
  
Synonyms : Cltc / Mus musculus clathrin, heavy polypeptide (Hc) (Cltc), transcript variant 1, mRNA. / Q68FD5
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 86694351
Gene end: 86757565
  
Corresponding Affymetrix probe sets: 10389526 (MoGene1.0st)   1439094_at (Mouse Genome 430 2.0 Array)   1454626_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050220
Ensembl peptide - ENSMUSP00000099475
Ensembl peptide - ENSMUSP00000117674
NCBI entrez gene - 67300     See in Manteia.
MGI - MGI:2388633
RefSeq - XM_006533985
RefSeq - NM_001003908
RefSeq - NM_001356393
RefSeq - XM_006533983
RefSeq - XM_006533984
RefSeq Peptide - NP_001003908
RefSeq Peptide - NP_001343322
swissprot - Q5SXR6
swissprot - Q68FD5
swissprot - F6Z1R4
Ensembl - ENSMUSG00000047126
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dhx34 / DExH-box helicase 34 / Q14147*ENSMUSG0000000601910
Dhx16 / DEAH-box helicase 16 / O60231*ENSMUSG000000244229
Dhx8 / A2A4P0 / ATP-dependent RNA helicase DHX8 / Q14562* / DEAH-box helicase 8*ENSMUSG000000349319
Dhx38 / DEAH-box helicase 38 / Q92620*ENSMUSG000000379939
Dhx40 / Q6PE54 / Probable ATP-dependent RNA helicase DHX40 / Q8IX18* / DEAH-box helicase 40*ENSMUSG000000184258
Dhx35 / probable ATP-dependent RNA helicase DHX35 isoform b / Q9H5Z1* / DEAH-box helicase 35*ENSMUSG000000276558
Dhx15 / O35286 / Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 / O43143* / DEAH-box helicase 15*ENSMUSG000000291698
Dhx33 / Q80VY9 / Putative ATP-dependent RNA helicase DHX33 / Q9H6R0* / DEAH-box helicase 33*ENSMUSG000000406208


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR012331  Clathrin, heavy chain, linker
 IPR015348  Clathrin, heavy chain, linker, core motif
 IPR016024  Armadillo-type fold
 IPR016341  Clathrin, heavy chain
 IPR022365  Clathrin, heavy chain, propeller repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle ISO
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006898 receptor-mediated endocytosis ISO
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0031623 receptor internalization ISO
 biological_processGO:0033572 transferrin transport ISO
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISO
 biological_processGO:0045056 transcytosis ISO
 biological_processGO:0048268 clathrin coat assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060236 regulation of mitotic spindle organization ISO
 biological_processGO:0072583 clathrin-dependent endocytosis ISO
 biological_processGO:0090307 mitotic spindle assembly ISO
 biological_processGO:1900126 negative regulation of hyaluronan biosynthetic process ISO
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005819 spindle ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IDA
 cellular_componentGO:0030118 clathrin coat ISO
 cellular_componentGO:0030130 clathrin coat of trans-Golgi network vesicle IEA
 cellular_componentGO:0030132 clathrin coat of coated pit IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISO
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031523 Myb complex ISO
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0071439 clathrin complex IEA
 cellular_componentGO:0072686 mitotic spindle ISO
 cellular_componentGO:1990498 mitotic spindle microtubule ISO
 molecular_functionGO:0003725 double-stranded RNA binding ISO
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0032051 clathrin light chain binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding ISO
 molecular_functionGO:0097718 disordered domain specific binding ISO
 molecular_functionGO:1990381 ubiquitin-specific protease binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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