ENSMUSG00000035239


Mus musculus

Features
Gene ID: ENSMUSG00000035239
  
Biological name :Neu3
  
Synonyms : Neu3 / neuraminidase 3 / Q9JMH7
  
Possible biological names infered from orthology : Q9UQ49
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E1
Gene start: 99811439
Gene end: 99828417
  
Corresponding Affymetrix probe sets: 10565840 (MoGene1.0st)   1419339_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045222
NCBI entrez gene - 50877     See in Manteia.
MGI - MGI:1355305
RefSeq - NM_016720
RefSeq Peptide - NP_057929
swissprot - Q543I9
swissprot - Q9JMH7
Ensembl - ENSMUSG00000035239
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neu3.1ENSDARG00000096382Danio rerio
 neu3.2ENSDARG00000010047Danio rerio
 neu3.3ENSDARG00000058327Danio rerio
 neu3.4ENSDARG00000096381Danio rerio
 neu3.5ENSDARG00000096368Danio rerio
 NEU3ENSGALG00000028960Gallus gallus
 NEU3ENSG00000162139Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Neu4 / Q8BZL1 / Sialidase-4 / Q8WWR8* / neuraminidase 4*ENSMUSG0000003400045
Neu2 / Q9JMH3 / Sialidase-2 / Q9Y3R4* / neuraminidase 2*ENSMUSG0000007943438


Protein motifs (from Interpro)
Interpro ID Name
 IPR011040  Sialidase
 IPR026856  Sialidase family
 IPR026944  Sialidase-3
 IPR036278  Sialidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process ISO
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006689 ganglioside catabolic process ISS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0004308 exo-alpha-sialidase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016997 alpha-sialidase activity IEA
 molecular_functionGO:0052794 exo-alpha-(2->3)-sialidase activity ISS
 molecular_functionGO:0052795 exo-alpha-(2->6)-sialidase activity IEA
 molecular_functionGO:0052796 exo-alpha-(2->8)-sialidase activity ISS


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pank1tm1.1Suja/Pank1tm1.1Suja,Pank2tm1.1Suja/Pank2tm1.1Suja
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pank1tm1.1Suja/Pank1tm1.1Suja,Pank2tm1.1Suja/Pank2tm1.1Suja
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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