ENSMUSG00000035725


Mus musculus

Features
Gene ID: ENSMUSG00000035725
  
Biological name :Prkx
  
Synonyms : cAMP-dependent protein kinase catalytic subunit PRKX / Prkx / Q922R0
  
Possible biological names infered from orthology : P51817 / protein kinase, X-linked
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: B
Gene start: 77761411
Gene end: 77796278
  
Corresponding Affymetrix probe sets: 10605465 (MoGene1.0st)   1424286_at (Mouse Genome 430 2.0 Array)   1424287_at (Mouse Genome 430 2.0 Array)   1451299_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045304
Ensembl peptide - ENSMUSP00000109678
NCBI entrez gene - 19108     See in Manteia.
MGI - MGI:1309999
RefSeq - XM_006527910
RefSeq - NM_016979
RefSeq - XM_006527909
RefSeq Peptide - NP_058675
swissprot - Q922R0
swissprot - B1AVU1
Ensembl - ENSMUSG00000035725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkxENSDARG00000060716Danio rerio
 PRKXENSGALG00000042759Gallus gallus
 PRKXENSG00000183943Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha / P17612* / protein kinase cAMP-activated catalytic subunit alpha*ENSMUSG0000000546948
P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*ENSMUSG0000000503447
Prkg1 / P0C605 / protein kinase, cGMP-dependent, type I / Q13976*ENSMUSG0000005292042
Prkg2 / protein kinase, cGMP-dependent, type II / Q13237*ENSMUSG0000002933441


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis ISO
 biological_processGO:0001935 endothelial cell proliferation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0060562 epithelial tube morphogenesis IEA
 biological_processGO:0060993 kidney morphogenesis IEA
 biological_processGO:2000696 regulation of epithelial cell differentiation involved in kidney development IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004691 cAMP-dependent protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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