ENSMUSG00000038225


Mus musculus

Features
Gene ID: ENSMUSG00000038225
  
Biological name :Primpol
  
Synonyms : DNA-directed primase/polymerase protein / Primpol / Q6P1E7
  
Possible biological names infered from orthology : primase and DNA directed polymerase / Q96LW4
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B1.1
Gene start: 46575594
Gene end: 46617212
  
Corresponding Affymetrix probe sets: 10578557 (MoGene1.0st)   1439788_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147458
Ensembl peptide - ENSMUSP00000147574
Ensembl peptide - ENSMUSP00000148164
Ensembl peptide - ENSMUSP00000148093
Ensembl peptide - ENSMUSP00000147684
Ensembl peptide - ENSMUSP00000036119
Ensembl peptide - ENSMUSP00000115987
NCBI entrez gene - 408022     See in Manteia.
MGI - MGI:3603756
RefSeq - XM_017312887
RefSeq - XM_006509459
RefSeq - XM_006509460
RefSeq - XM_006509461
RefSeq - XM_006509462
RefSeq - XM_006509464
RefSeq - XM_011242229
RefSeq - NM_001001184
RefSeq - XM_006509458
RefSeq Peptide - NP_001001184
swissprot - A0A1B0GT20
swissprot - A0A1B0GRW0
swissprot - A0A1B0GRB9
swissprot - D3YXL5
swissprot - Q6P1E7
Ensembl - ENSMUSG00000038225
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q32PL8ENSDARG00000033273Danio rerio
 PRIMPOLENSGALG00000010636Gallus gallus
 Q96LW4ENSG00000164306Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006264 mitochondrial DNA replication IEA
 biological_processGO:0006269 DNA replication, synthesis of RNA primer IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0019985 translesion synthesis IEA
 biological_processGO:0031297 replication fork processing IEA
 biological_processGO:0032774 RNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix ISO
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity ISO
 molecular_functionGO:0003896 DNA primase activity IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Adamts6b2b2407Clo/Adamts6b2b2407Clo
Genetic Background: C57BL/6J-Adamts6b2b2407Clo

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Fbn2fp-4J/Fbn2fp-4J
Genetic Background: BALB/cByJ-Fbn2fp-4J/GrsrJ

 MP:0004815 abnormal somatic hypermutation frequency "any anomaly in the high frequency of programmed mutation that occurs in the gene segments encoding the variable regions of antibodies during the differentiation of individual B lymphocytes into antibody producing plasma cells " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Egfrwa2/Egfrwa2
Genetic Background: involves: C57BL/6

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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