ENSMUSG00000038241


Mus musculus

Features
Gene ID: ENSMUSG00000038241
  
Biological name :Cep250
  
Synonyms : Centrosome-associated protein CEP250 / Cep250 / Q60952
  
Possible biological names infered from orthology : centrosomal protein 250 / Q9BV73
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 155956458
Gene end: 155998900
  
Corresponding Affymetrix probe sets: 10477739 (MoGene1.0st)   1421512_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114426
Ensembl peptide - ENSMUSP00000105248
Ensembl peptide - ENSMUSP00000119845
Ensembl peptide - ENSMUSP00000122223
Ensembl peptide - ENSMUSP00000038255
Ensembl peptide - ENSMUSP00000091988
Ensembl peptide - ENSMUSP00000105247
NCBI entrez gene - 16328     See in Manteia.
MGI - MGI:108084
RefSeq - XM_017315701
RefSeq - NM_001129999
RefSeq - NM_001130000
RefSeq - NM_008383
RefSeq - NM_177217
RefSeq - XM_006498796
RefSeq - XM_006498797
RefSeq - XM_006498798
RefSeq - XM_006498799
RefSeq Peptide - NP_796191
RefSeq Peptide - NP_001123472
RefSeq Peptide - NP_032409
RefSeq Peptide - NP_001123471
swissprot - B7ZCN3
swissprot - Q60952
swissprot - Q8BZX9
swissprot - A3KGJ7
swissprot - E9Q5A8
swissprot - F6QCB4
swissprot - F7BUJ0
Ensembl - ENSMUSG00000038241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-230p4.1ENSDARG00000020834Danio rerio
 CEP250ENSGALG00000026151Gallus gallus
 CEP250ENSG00000126001Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crocc / Q8CJ40 / Rootletin / Q5TZA2* / ciliary rootlet coiled-coil, rootletin*ENSMUSG0000004086023
Crocc2 / ciliary rootlet coiled-coil, rootletin family member 2 / H7BZ55*ENSMUSG0000008498916


Protein motifs (from Interpro)
Interpro ID Name
 IPR026048  Centrosome-associated protein CEP250


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle ISO
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008104 protein localization ISO
 biological_processGO:0010457 centriole-centriole cohesion ISO
 biological_processGO:0030997 regulation of centriole-centriole cohesion ISO
 biological_processGO:0033365 protein localization to organelle ISO
 biological_processGO:1904781 positive regulation of protein localization to centrosome ISO
 biological_processGO:1905515 non-motile cilium assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0031616 spindle pole centrosome IDA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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