ENSMUSG00000040860


Mus musculus

Features
Gene ID: ENSMUSG00000040860
  
Biological name :Crocc
  
Synonyms : Crocc / Q8CJ40 / Rootletin
  
Possible biological names infered from orthology : ciliary rootlet coiled-coil, rootletin / Q5TZA2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 141016637
Gene end: 141060550
  
Corresponding Affymetrix probe sets: 10517842 (MoGene1.0st)   1427338_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095425
Ensembl peptide - ENSMUSP00000120555
Ensembl peptide - ENSMUSP00000126543
Ensembl peptide - ENSMUSP00000037679
Ensembl peptide - ENSMUSP00000099549
NCBI entrez gene - 230872     See in Manteia.
MGI - MGI:3529431
RefSeq - XM_006538802
RefSeq - NM_001145958
RefSeq - NM_172122
RefSeq - XM_006538800
RefSeq - XM_006538801
RefSeq Peptide - NP_001139430
RefSeq Peptide - NP_742120
swissprot - Q8CJ40
swissprot - B7ZC90
Ensembl - ENSMUSG00000040860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039329Gallus gallus
 CROCCENSG00000058453Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crocc2 / ciliary rootlet coiled-coil, rootletin family member 2 / H7BZ55*ENSMUSG0000008498929
Cep250 / Q60952 / Centrosome-associated protein CEP250 / Q9BV73* / centrosomal protein 250*ENSMUSG0000003824128


Protein motifs (from Interpro)
Interpro ID Name
 IPR026733  Rootletin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle ISS
 biological_processGO:0008104 protein localization ISO
 biological_processGO:0010457 centriole-centriole cohesion ISO
 biological_processGO:0010669 epithelial structure maintenance IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0032053 ciliary basal body organization IMP
 biological_processGO:0033365 protein localization to organelle ISO
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0045724 positive regulation of cilium assembly ISO
 biological_processGO:0051656 establishment of organelle localization IMP
 biological_processGO:1903566 positive regulation of protein localization to cilium ISO
 cellular_componentGO:0001917 photoreceptor inner segment IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0035253 ciliary rootlet IMP
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IDA
 molecular_functionGO:0005198 structural molecule activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Dlg4tm1Grnt/Dlg4tm1Grnt,Syngap1tm1Grnt/Syngap1+
Genetic Background: involves: 129P2/OlaHsd * MF1

 MP:0008450 retinal photoreceptor degeneration "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dlg4tm1Grnt/Dlg4tm1Grnt,Syngap1tm1Grnt/Syngap1+
Genetic Background: involves: 129P2/OlaHsd * MF1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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