ENSMUSG00000038291


Mus musculus

Features
Gene ID: ENSMUSG00000038291
  
Biological name :Snx25
  
Synonyms : Q3ZT31 / Snx25 / Sorting nexin-25
  
Possible biological names infered from orthology : Q9H3E2
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B1.1
Gene start: 46033261
Gene end: 46152159
  
Corresponding Affymetrix probe sets: 10578521 (MoGene1.0st)   1455020_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106007
Ensembl peptide - ENSMUSP00000148177
Ensembl peptide - ENSMUSP00000134949
Ensembl peptide - ENSMUSP00000127640
Ensembl peptide - ENSMUSP00000035785
Ensembl peptide - ENSMUSP00000106006
NCBI entrez gene - 102141     See in Manteia.
MGI - MGI:2142610
RefSeq - XM_017312502
RefSeq - NM_207213
RefSeq - XM_006509242
RefSeq - XM_006509243
RefSeq Peptide - NP_997096
swissprot - E9Q1K0
swissprot - Q3ZT31
swissprot - A0A1B0GT31
swissprot - H3BJE1
swissprot - D3Z040
Ensembl - ENSMUSG00000038291
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx25ENSDARG00000099545Danio rerio
 SNX25ENSGALG00000010610Gallus gallus
 SNX25ENSG00000109762Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snx13 / sorting nexin 13 / Q9Y5W8*ENSMUSG0000002059025
Snx14 / Q8BHY8 / Sorting nexin-14 / Q9Y5W7*ENSMUSG0000003242218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR003114  Phox-associated domain
 IPR013937  Sorting nexin, C-terminal
 IPR016137  RGS domain
 IPR034905  Sorting nexin-25
 IPR036305  RGS domain superfamily
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0032801 receptor catabolic process ISO
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding IPI
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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