ENSMUSG00000038400


Mus musculus

Features
Gene ID: ENSMUSG00000038400
  
Biological name :Pmepa1
  
Synonyms : Pmepa1 / prostate transmembrane protein, androgen induced 1
  
Possible biological names infered from orthology : Q969W9
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 173224458
Gene end: 173276533
  
Corresponding Affymetrix probe sets: 10490159 (MoGene1.0st)   1422705_at (Mouse Genome 430 2.0 Array)   1422706_at (Mouse Genome 430 2.0 Array)   1452295_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039950
Ensembl peptide - ENSMUSP00000115534
NCBI entrez gene - 65112     See in Manteia.
MGI - MGI:1929600
RefSeq - NM_022995
RefSeq - XM_006499991
RefSeq Peptide - NP_075371
swissprot - A2APF5
swissprot - A2APF4
Ensembl - ENSMUSG00000038400
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PMEPA1ENSG00000124225Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BWJ4 / Ldlrad4 / Low-density lipoprotein receptor class A domain-containing protein 4 / O15165* / low density lipoprotein receptor class A domain containing 4*ENSMUSG0000002454459


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010991 negative regulation of SMAD protein complex assembly IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0050699 WW domain binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of TGF-beta receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024563 Smad2 / Q62432 / Mothers against decapentaplegic homolog 2 / Q15796* / SMAD family member 2*  / complex / reaction
 ENSMUSG00000032402 Smad3 / Q8BUN5 / Mothers against decapentaplegic homolog 3 / P84022* / SMAD family member 3*  / complex / reaction






 

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