ENSMUSG00000038526


Mus musculus

Features
Gene ID: ENSMUSG00000038526
  
Biological name :Car14
  
Synonyms : Car14 / Mus musculus carbonic anhydrase 14 (Car14), transcript variant 2, mRNA. / Q9WVT6
  
Possible biological names infered from orthology : CA14 / carbonic anhydrase 14 / Q9ULX7
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.1
Gene start: 95897768
Gene end: 95904691
  
Corresponding Affymetrix probe sets: 10500283 (MoGene1.0st)   1450725_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036983
Ensembl peptide - ENSMUSP00000117464
NCBI entrez gene - 23831     See in Manteia.
MGI - MGI:1344341
RefSeq - XM_017319568
RefSeq - NM_001355750
RefSeq - NM_001355751
RefSeq - NM_011797
RefSeq - XM_006501442
RefSeq - XM_006501443
RefSeq - XM_017319567
RefSeq Peptide - NP_001342679
RefSeq Peptide - NP_001342680
RefSeq Peptide - NP_035927
swissprot - Q9WVT6
swissprot - D3Z4J8
Ensembl - ENSMUSG00000038526
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca14ENSDARG00000061697Danio rerio
 CA14ENSG00000118298Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Car9 / Q8VHB5 / Carbonic anhydrase 9 / CA9* / Q16790*ENSMUSG0000002846339
Car12 / carbonic anhydrase 12 / CA12* / O43570*ENSMUSG0000003237338
Car7 / Q9ERQ8 / Carbonic anhydrase 7 / CA7* / P43166*ENSMUSG0000003188329
Car15 / Q99N23 / Carbonic anhydrase 15 ENSMUSG0000009023629
Car4 / Q64444 / Carbonic anhydrase 4 / CA4* / P22748*ENSMUSG0000000080528
Car13 / Q9D6N1 / Carbonic anhydrase 13 / CA13* / Q8N1Q1*ENSMUSG0000002755528
Car2 / P00920 / Mus musculus carbonic anhydrase 2 (Car2), transcript variant 2, mRNA. / CA2* / P00918* / carbonic anhydrase 2*ENSMUSG0000002756228
Car1 / P13634 / Carbonic anhydrase 1 / CA1* / P00915*ENSMUSG0000002755627
Car3 / P16015 / Carbonic anhydrase 3 / CA3* / P07451*ENSMUSG0000002755926
Car6 / P18761 / Carbonic anhydrase 6 / CA6* / P23280*ENSMUSG0000002897226
Car5b / Q9QZA0 / Carbonic anhydrase 5B, mitochondrial / CA5B* / Q9Y2D0* / carbonic anhydrase 5B*ENSMUSG0000003137325
Car5a / P23589 / Carbonic anhydrase 5A, mitochondrial / CA5A* / P35218* / carbonic anhydrase 5A*ENSMUSG0000002531724
Car8 / P28651 / Carbonic anhydrase-related protein / CA8* / P35219* / carbonic anhydrase 8*ENSMUSG0000004126123


Protein motifs (from Interpro)
Interpro ID Name
 IPR001148  Alpha carbonic anhydrase domain
 IPR018431  Carbonic anhydrase, CA14
 IPR023561  Carbonic anhydrase, alpha-class
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006885 regulation of pH IC
 biological_processGO:0015670 carbon dioxide transport IC
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004089 carbonate dehydratase activity IMP
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reversible hydration of carbon dioxide


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004043 abnormal pH regulation "anomaly in the function of the buffer systems of the body in combination with the respiratory and renal systems that control the relative acidity or alkalinity of the body, as measured by the concentration of hydrogen ion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Car14tm1Sly/Car14tm1Sly,Car4tm1Sly/Car4tm1Sly
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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