MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Qkqk-2J/Qkqk-shk Genetic Background: involves: 129 * C57BL/6 * C57BLKS/J
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MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Qkqk-2J/Qkqk-shk Genetic Background: involves: 129 * C57BL/6 * C57BLKS/J
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MP:0001363 | increased anxiety-related response | "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060] |
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Allelic Composition: Dnmt1tm2Jrc/Dnmt1tm2Jrc Genetic Background: involves: 129S1/Sv
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MP:0002573 | behavioral despair | "depression assayed by reduced escape attempts and/or immobility when placed in a stressful situation such as a forced swim test or a suspension test; or failure to seek pleasurable stimuli" [J:80395] |
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Allelic Composition: Dnmt1tm2Jrc/Dnmt1tm2Jrc Genetic Background: involves: 129S1/Sv
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MP:0003351 | decreased circulating levels of thyroid hormone | "reduced concentration of hormones in the blood that are synthesized and secreted by the thyroid" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003503 | decreased activity of thyroid | |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005121 | decreased circulating prolactin level | "less than expected blood concentration of the hormone that stimulates milk secretion " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor Genetic Background: involves: 129X1/SvJ
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MP:0005289 | increased oxygen consumption | "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Qkqk-2J/Qkqk-shk Genetic Background: involves: 129 * C57BL/6 * C57BLKS/J
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MP:0005471 | decreased thyroxine level | "less than the normal concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:13923] |
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor Genetic Background: involves: 129X1/SvJ
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MP:0005473 | decreased triiodothyronine level | "less than the normal concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor Genetic Background: involves: 129X1/SvJ
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MP:0005478 | decreased circulating thyroxine level | "less than the normal blood concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dnmt1tm2Jrc/Dnmt1tm2Jrc Genetic Background: involves: 129S1/Sv
Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005479 | decreased circulating triiodothyronine level | "less than the normal blood concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Dnmt1tm2Jrc/Dnmt1tm2Jrc Genetic Background: involves: 129S1/Sv
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MP:0011611 | abnormal circulating ghrelin level | "any anomaly in the blood concentration of the peptide hormone produced mainly by P/D1 cells lining the fundus of the stomach and epsilon cells of the pancreas that stimulates hunger and serves as a potent stimulator of growth hormone from the anterior pituitary gland; in addition to stimulating appetite and growth, ghrelin also plays various roles in energy homeostasis, neuropathy, and in the cardiovascular and immune systems" [MGI:anna] |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011612 | increased circulating ghrelin level | "greater than the normal blood concentration of the peptide hormone produced mainly by P/D1 cells lining the fundus of the stomach and epsilon cells of the pancreas that normally stimulates hunger and serves as a potent stimulator of growth hormone from the anterior pituitary gland" [MGI:anna] |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011613 | decreased circulating ghrelin level | "less than the normal blood concentration of the peptide hormone produced mainly by P/D1 cells lining the fundus of the stomach and epsilon cells of the pancreas that normally stimulates hunger and serves as a potent stimulator of growth hormone from the anterior pituitary gland" [MGI:anna] |
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Allelic Composition: Trhrtm1Bau/Trhrtm1Bau Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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