ENSMUSG00000039628


Mus musculus
sulfotransferasemembraneactivityHs3st6heparansulfategolgicomponentdomainp-loopcontainingnucleosidetriphosphatehydrolasecellularapparatusintegral-glucosamine-sulfotransferasetransferasehs-gagbiosynthesis

Features
Gene ID: ENSMUSG00000039628
  
Biological name :Hs3st6
  
Synonyms : Heparan sulfate glucosamine 3-O-sulfotransferase 6 / Hs3st6 / Q5GFD5
  
Possible biological names infered from orthology : heparan sulfate-glucosamine 3-sulfotransferase 6 / Q96QI5
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 24753003
Gene end: 24758683
  
Corresponding Affymetrix probe sets: 10442603 (MoGene1.0st)   1459646_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040919
NCBI entrez gene - 328779     See in Manteia.
MGI - MGI:3580487
RefSeq - XM_006524426
RefSeq - NM_001012402
RefSeq - XM_006524425
RefSeq Peptide - NP_001012402
swissprot - Q5GFD5
swissprot - A2RTI7
Ensembl - ENSMUSG00000039628
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-121b10.7ENSDARG00000059948Danio rerio
 HS3ST6ENSGALG00000005413Gallus gallus
 HS3ST6ENSG00000162040Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BKN6 / Hs3st3a1 / Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 / Q9Y662* / HS3ST3B1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1*ENSMUSG0000004775963
Q9QZS6 / Hs3st3b1 / Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 / Q9Y662* / heparan sulfate-glucosamine 3-sulfotransferase 3B1*ENSMUSG0000007040760
Hs3st2 / Q673U1 / Heparan sulfate glucosamine 3-O-sulfotransferase 2 / Q9Y278* / heparan sulfate-glucosamine 3-sulfotransferase 2*ENSMUSG0000004632157
Hs3st4 / heparan sulfate-glucosamine 3-sulfotransferase 4 / Q9Y661*ENSMUSG0000007859156
Hs3st5 / Q8BSL4 / heparan sulfate (glucosamine) 3-O-sulfotransferase 5 / Q8IZT8* / heparan sulfate-glucosamine 3-sulfotransferase 5*ENSMUSG0000004449935
Hs3st1 / O35310 / Heparan sulfate glucosamine 3-O-sulfotransferase 1 / O14792* / heparan sulfate-glucosamine 3-sulfotransferase 1*ENSMUSG0000005102234
Ndst2 / P52850 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 / P52849* / AC022400.6* / N-deacetylase and N-sulfotransferase 2* / bifunctional heparan sulfate N-deacetylase/N-s...ENSMUSG0000003930826
Ndst1 / Q3UHN9 / Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Heparan sulfate N-deacetylase 1 Heparan sulfate N-sulfotransferase 1 / P52848* / N-deacetylase and N-sulfotr...ENSMUSG0000005400826
Ndst4 / Q9EQW8 / Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 Heparan sulfate N-deacetylase 4 Heparan sulfate N-sulfotransferase 4 / Q9H3R1* / N-deacetylase and N-sulfotr...ENSMUSG0000002797125
Ndst3 / Q9EQH7 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 / O95803* / N-deacetylase and N-sulfotransferase 3*ENSMUSG0000002797725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
transferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activity
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity IDA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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