ENSMUSG00000039648


Mus musculus

Features
Gene ID: ENSMUSG00000039648
  
Biological name :Kyat1
  
Synonyms : Kyat1 / Mus musculus kynurenine aminotransferase 1 (Kyat1), transcript variant 2, mRNA. / Q8BTY1
  
Possible biological names infered from orthology : kynurenine aminotransferase 1 / Q16773
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 30185124
Gene end: 30205847
  
Corresponding Affymetrix probe sets: 10481435 (MoGene1.0st)   1428151_x_at (Mouse Genome 430 2.0 Array)   1438348_x_at (Mouse Genome 430 2.0 Array)   1446302_at (Mouse Genome 430 2.0 Array)   1452678_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109292
Ensembl peptide - ENSMUSP00000109291
Ensembl peptide - ENSMUSP00000109293
Ensembl peptide - ENSMUSP00000038612
Ensembl peptide - ENSMUSP00000109289
Ensembl peptide - ENSMUSP00000109290
NCBI entrez gene - 70266     See in Manteia.
MGI - MGI:1917516
RefSeq - XM_006498318
RefSeq - NM_001356474
RefSeq - NM_172404
RefSeq - XM_006498314
RefSeq - XM_006498315
RefSeq - XM_006498317
RefSeq Peptide - NP_001343403
RefSeq Peptide - NP_765992
swissprot - Q05CI8
swissprot - A2AQY9
swissprot - Q8BTY1
swissprot - A2AQY8
Ensembl - ENSMUSG00000039648
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kyat1ENSDARG00000023645Danio rerio
 ENSGALG00000004604Gallus gallus
 KYAT1ENSG00000171097Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kyat3 / Q71RI9 / Kynurenine--oxoglutarate transaminase 3 / Q6YP21* / kynurenine aminotransferase 3*ENSMUSG0000004021350
Tat / Q8QZR1 / tyrosine aminotransferase / P17735*ENSMUSG0000000167021


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR034614  Kynurenine--oxoglutarate transaminase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006575 cellular modified amino acid metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0070189 kynurenine metabolic process IEA
 biological_processGO:0097052 L-kynurenine metabolic process IEA
 biological_processGO:0097053 L-kynurenine catabolic process IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016212 kynurenine-oxoglutarate transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0047312 L-phenylalanine:pyruvate aminotransferase activity ISO
 molecular_functionGO:0047316 glutamine-phenylpyruvate transaminase activity IEA
 molecular_functionGO:0047804 cysteine-S-conjugate beta-lyase activity IEA
 molecular_functionGO:0047945 L-glutamine:pyruvate aminotransferase activity ISO
 molecular_functionGO:0070548 L-glutamine aminotransferase activity IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)
Phenylalanine and tyrosine catabolism
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039648 Kyat1 / Q8BTY1 / Mus musculus kynurenine aminotransferase 1 (Kyat1), transcript variant 2, mRNA. / Q16773* / kynurenine aminotransferase 1*  / complex






 

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