ENSMUSG00000041605


Mus musculus

Features
Gene ID: ENSMUSG00000041605
  
Biological name :5730559C18Rik
  
Synonyms : 5730559C18Rik / innate immunity activator
  
Possible biological names infered from orthology : INAVA / Q3KP66
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 136213531
Gene end: 136234264
  
Corresponding Affymetrix probe sets: 10358177 (MoGene1.0st)   1436345_at (Mouse Genome 430 2.0 Array)   1450559_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113785
Ensembl peptide - ENSMUSP00000141506
Ensembl peptide - ENSMUSP00000120263
Ensembl peptide - ENSMUSP00000118074
Ensembl peptide - ENSMUSP00000115554
NCBI entrez gene - 67313     See in Manteia.
MGI - MGI:1921579
RefSeq - XM_006529806
RefSeq - NM_028872
RefSeq - XM_006529802
RefSeq - XM_006529803
RefSeq - XM_006529804
RefSeq - XM_006529805
RefSeq Peptide - NP_083148
swissprot - D3YZL7
swissprot - A0A0A6YWD6
swissprot - G3X9Z8
swissprot - D3YZT8
swissprot - D6RJ44
Ensembl - ENSMUSG00000041605
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INAVAENSDARG00000078155Danio rerio
 zgc:153953ENSDARG00000070571Danio rerio
 INAVAENSGALG00000044612Gallus gallus
 INAVAENSG00000163362Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Frmd4a / Q8BIE6 / Mus musculus FERM domain containing 4A (Frmd4a), transcript variant 4, mRNA. / Q9P2Q2* / FERM domain containing 4A*ENSMUSG0000002665730
Frmd4b / Q920B0 / Mus musculus FERM domain containing 4B (Frmd4b), transcript variant 2, mRNA. / Q9Y2L6* / FERM domain containing 4B*ENSMUSG0000003006423
A2AEV7 / Ccdc120 / Coiled-coil domain-containing protein 120 / Q96HB5* / coiled-coil domain containing 120*ENSMUSG0000003115019


Protein motifs (from Interpro)
Interpro ID Name
 IPR021774  Domain of unknown function DUF3338


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0002221 pattern recognition receptor signaling pathway IEA
 biological_processGO:0002367 cytokine production involved in immune response IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032494 response to peptidoglycan IEA
 biological_processGO:0032495 response to muramyl dipeptide IEA
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IEA
 biological_processGO:0032733 positive regulation of interleukin-10 production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0034334 adherens junction maintenance IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway IEA
 biological_processGO:1903409 reactive oxygen species biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptentm1Rdp/Ptentm1Rdp,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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